PTPRE Antibodies

AND PTPRE ELISA kits, PTPRE Proteins

Many biological assays use antibodies to detect PTPRE, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRE in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRE antibodies...

We validate the specificity of these antibodies to PTPRE by testing them on tissues known to express PTPRE positively and negatively. Browse below to find the PTPRE antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPRE Infographic by Boster Bio

All PTPRE Products

Product

Figures

Specificity

Applications

Price

Anti-PTPRE Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A05574
100ul

PTP epsilon (PTPRE) (NM_006504) Human Recombinant Protein

$1249
Cat # PROTP23469
20 µg

Anti-PTP epsilon (PTPRE) Mouse Monoclonal Antibody [Clone ID: OTI3D4]

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M05574
100 µl

PTP epsilon (PTPRE) (NM_006504) Human Over-expression Lysate

Human

$628
Cat # LS005791
100 µg

PTPRE Overview

Facts about Receptor-type tyrosine-protein phosphatase epsilon.

PTPRE 3D structure. Source: alphafold

Receptor-type tyrosine-protein phosphatase epsilon (PTPRE)

Isoform 1 plays a vital role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).

. .

Gene Information

Human
Gene Name:	PTPRE
Uniprot:	P23469
Entrez:	5791

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

DKFZp313F1310; EC 3.1.3.48; FLJ57799; FLJ58245; HPTPE; protein tyrosine phosphatase epsilon; protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein-tyrosine phosphatase epsilon; PTPE; receptor-type tyrosine-protein phosphatase epsilon; R-PTP-EPSILON

Molecular Weight

Mass (kDA):
80.642 kDA

Genomic Context


Human

Location:	10q26.2
Sequence:	10; NC_000010.11 (127907053..128085855)

Tissue Specificity

Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells).

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm. Predominantly cytoplasmic. A small fraction is also associated with nucleus and membrane. Insulin induces translocation to the membrane (By similarity).; [Isoform 3]: Cytoplasm.

Diseases

Posttransfusion Purpura
Neoplasms
Malignant Neoplasms
Inflammation
Mammary Neoplasms
Nervousness
Tissue Adhesions
Leukemia
Carcinoma
Pathologic Neovascularization
Mammary Neoplasms, Experimental
Allergic Asthma

Malignant Paraganglionic Neoplasm
Growth Arrest
Acute Erythroblastic Leukemia
Animal Mammary Neoplasms
Asthma
Janiceps
Disease Of Adrenal Medulla

Pathways

Localization
Cell Growth
Transport
Myelination
Cell Differentiation
Cell Proliferation
Cytokine Production
Rna Processing
Secretion
Osteoclast Differentiation
Hyperphosphorylation
Immune Response
Endothelial Cell Proliferation

Reverse Transcription
Chemotaxis
Translation
Cell Cycle
Hemostasis
Oligodendrocyte Differentiation
Oncogenesis

PTMs

Phosphorylation
Dephosphorylation

Cleavage
Methylation

Research Areas

GPCR
Protein Phosphatase
Tyrosine Kinases

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPRE

References

PMID: 2170109 by Krueger N.X., et al. Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

PMID: 12121439 by Wabakken T.K., et al. Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase.