PTPN12 Antibodies

AND PTPN12 ELISA kits, PTPN12 Proteins

Many biological assays use antibodies to detect PTPN12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPN12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPN12 antibodies...

We validate the specificity of these antibodies to PTPN12 by testing them on tissues known to express PTPN12 positively and negatively. Browse below to find the PTPN12 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: PTPN13

PTPN12 Infographic by Boster Bio

All PTPN12 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PTN12 PTPN12 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A02762
100ul

Anti-PTPN12 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A02762-1
100 μg/vial

PTPN12 (NM_002835) Human Over-expression Lysate

Human

$628
Cat # LS005782
100 µg

PTPN12 Overview

Facts about Tyrosine-protein phosphatase non-receptor type 12.

PTPN12 3D structure. Source: alphafold

Tyrosine-protein phosphatase non-receptor type 12 (PTPN12)

Dephosphorylates a range of proteins, and thereby modulates cellular signaling cascades (PubMed:18559503). Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2 (PubMed:17329398, PubMed:27134172).

Selectively dephosphorylates ERBB2 phosphorylated in'Tyr-1112','Tyr-1196', and/or'Tyr-1248' (PubMed:27134172). .

Gene Information

Human
Gene Name:	PTPN12
Uniprot:	Q05209
Entrez:	5782

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

protein tyrosine phosphatase, non-receptor type 12; Protein-tyrosine phosphatase G1; PTPG1tyrosine-protein phosphatase non-receptor type 12; PTP-PESTEC 3.1.3.48

Molecular Weight

Mass (kDA):
88.106 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (77537190..77640069)

Subcellular Localizations

Cytoplasm. Cell junction, focal adhesion. Cell projection, podosome. Partial translocation to focal adhesion sites may be mediated by interaction with SORBS2.