PTP4A1 Antibodies

AND PTP4A1 ELISA kits, PTP4A1 Proteins

Many biological assays use antibodies to detect PTP4A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTP4A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTP4A1 antibodies...

We validate the specificity of these antibodies to PTP4A1 by testing them on tissues known to express PTP4A1 positively and negatively. Browse below to find the PTP4A1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTP4A1 Infographic by Boster Bio

All PTP4A1 Products

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Specificity

Applications

Price

Anti-TP4A1 PTP4A1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04417
100ul

PTP4A1 (NM_003463) Human Recombinant Protein

$813
Cat # PROTQ93096
20 µg

PTP4A1 (NM_003463) Human Over-expression Lysate

Human

$628
Cat # LS007803
100 µg

PTP4A1 Overview

Facts about Protein tyrosine phosphatase type IVA 1.

PTP4A1 3D structure. Source: alphafold

Protein tyrosine phosphatase type IVA 1 (PTP4A1)

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues.

Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. .

Gene Information

Human
Gene Name:	PTP4A1
Uniprot:	Q93096
Entrez:	7803

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; HH72; PRL1; PRL-1; PRL-1DKFZp779M0721; Protein tyrosine phosphatase IVA1; protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA protein 1; protein tyrosine phosphatase type IVA, member 1; Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PTP(CAAX1); PTP(CAAXI); PTPCAAX1PRL1PTP(CAAX1)

Molecular Weight

Mass (kDA):
19.815 kDA

Genomic Context


Human

Location:	6q12
Sequence:	6; NC_000006.12 (63528021..63583588)

Tissue Specificity

Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines.

Subcellular Localizations

Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. And mitotic spindle.

Diseases

Neoplasm Metastasis
Malignant Neoplasms
Neoplasms
Neoplasm Invasiveness
Carcinoma
Cell Invasion
Liver Regeneration Disorder
Posttransfusion Purpura
Tissue Adhesions
Metastatic Malignant Neoplasm To The Lymph Node
Adenocarcinoma
Colorectal Cancer
Cell Transformation, Neoplastic

Lung Neoplasms
Lymphatic Metastasis
Liver Carcinoma
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Paraganglionic Neoplasm

Interacting Proteins

CNNM1

Pathways

Localization
Regeneration
Cell Growth
Liver Regeneration
Cell Migration
Cell Proliferation
Prenylation
Cell Cycle
Cell Motility
Cell Adhesion
Cellular Localization
Developmental Process
Fertilization

Regulation Of Gene Expression
Liver Development
Spermatogenesis
Anaphase
Cell Cycle Arrest
Response To Oxidative Stress
Cell Division

PTMs

Prenylation
Phosphorylation
Farnesylation
Dephosphorylation

Oxidation
Biotinylation
Reduction
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTP4A1

References

PMID: 9018080 by Cates C.A., et al. Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases.

PMID: 9642300 by Peng Y., et al. The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer.