PTK7 Antibodies

AND PTK7 ELISA kits, PTK7 Proteins

Many biological assays use antibodies to detect PTK7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTK7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTK7 antibodies...

We validate the specificity of these antibodies to PTK7 by testing them on tissues known to express PTK7 positively and negatively. Browse below to find the PTK7 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTK7 Infographic by Boster Bio

All PTK7 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CCK-4 PTK7 Monoclonal Antibody

5 Q&As

Human

IHC, WB

$399
Cat # A02957
100μl

Anti-PTK7 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A02957-1
0.1 mg

CCK4 (PTK7) (NM_152881) Human Recombinant Protein

$1249
Cat # PROTQ13308
20 µg

Anti-CCK4 (PTK7) Antibody (N-term)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A02957-2
80 µl

Anti-CCK4 (PTK7) Mouse Monoclonal Antibody [Clone ID: OTI2E7]

Human, Mouse

Flow Cytometry, IF, WB

$523
Cat # M02957
100 µl

CCK4 (PTK7) (NM_152881) Human Over-expression Lysate

Human

$960
Cat # LS005754
100 µg

PTK7 Overview

Facts about Inactive tyrosine-protein kinase 7.

PTK7 3D structure. Source: alphafold

Inactive tyrosine-protein kinase 7 (PTK7)

Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also referred to as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.

Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Gene Information

Human
Gene Name:	PTK7
Uniprot:	Q13308
Entrez:	5754

Family

Belongs to:

protein kinase superfamily

Alternative Names

CCK4; CCK-4; CCK4Colon carcinoma kinase 4; colon carcinoma kinase-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; PTK7 protein tyrosine kinase 7; PTK7; Tyrosine-protein kinase-like 7

Molecular Weight

Mass (kDA):
118.392 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (43076314..43161720)

Tissue Specificity

Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Cell junction. Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.

Diseases

Malignant Neoplasms
Neoplasms
Leukemia
Tissue Adhesions
Malignant Neoplasm Of Stomach
Carcinoma
Cell Invasion
Malignant Tumor Of Colon
Acute Lymphocytic Leukemia
Stomach Neoplasms
Neoplasm Metastasis
Malignant Paraganglionic Neoplasm

Precursor T-cell Lymphoblastic Leukemia-lymphoma
Myeloid Leukemia
Congenital Abnormality
Colonic Neoplasms
Leukemia, Myelocytic, Acute
Colorectal Cancer
Melanoma

Interacting Proteins

CTNNB1

Pathways

Neural Tube Closure
Tube Closure
Localization
Convergent Extension
Cell Adhesion
Cell Migration
Proteolysis
Cell Motility
Gastrulation
Cell Proliferation
Lung Development
Axon Guidance
Cell Cycle

Embryonic Morphogenesis
Cell Death
Angiogenesis
Gene Silencing
Tube Formation
Stem Cell Maintenance
Embryo Development

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTK7

References

PMID: 7478540 by Mossie K., et al. Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family.

PMID: 8882711 by Park S.-K., et al. Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG.