PTH2 Antibodies

AND PTH2 ELISA kits, PTH2 Proteins

Many biological assays use antibodies to detect PTH2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTH2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTH2 antibodies...

We validate the specificity of these antibodies to PTH2 by testing them on tissues known to express PTH2 positively and negatively. Browse below to find the PTH2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTH2 Infographic by Boster Bio

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Tuberoinfundibular peptide (PTH2) (NM_178449) Human Recombinant Protein

$813
Cat # PROTQ96A98
20 µg

Tuberoinfundibular peptide (PTH2) (NM_178449) Human Over-expression Lysate

Human

$628
Cat # LS113091
100 µg

PTH2 Overview

Facts about Tuberoinfundibular peptide of 39 residues.

PTH2 3D structure. Source: alphafold

Tuberoinfundibular peptide of 39 residues (PTH2)

Plays a role as a potent and selective agonist of PTH2R leading to adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization.

May inhibit cell proliferation via its actions on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis.

Gene Information

Human
Gene Name:	PTH2
Uniprot:	Q96A98
Entrez:	113091

Family

Belongs to:

parathyroid hormone family

Alternative Names

parathyroid hormone 2TIP39tuberoinfundibular 39 residue protein; TIPF39; tuberoinfundibular 39 residues; tuberoinfundibular peptide of 39 residues

Molecular Weight

Mass (kDA):
11.202 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49422419..49423441, complement)

Tissue Specificity

Highly expressed in fetal and adult brain, cerebellum and trachea. Weakly expressed in spinal cord, fetal liver, kidney and heart.

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Nervousness
Carcinoma
Central Nervous System Neoplasms
Hypocalcemia
Tissue Adhesions
Basal Cell Carcinoma
Neoplasm Metastasis
Melanoma
Glioma
Anaplastic Astrocytoma

Malignant Neoplasm Of Lung
Degenerative Polyarthritis
Severe Combined Immunodeficiency
Cytomegalovirus Infections
Pain
Malignant Neoplasm Of Ovary
Lymphoma

Pathways

Cell Death
Anoikis
Localization
Translation
Rna Interference
Secretion
Cell Adhesion
Gene Silencing By Rna
Translational Initiation
Gene Silencing
Proteolysis

Virulence
Response To Acetate
Long-term Memory
Aldosterone Secretion
Regulation Of Anoikis
Bone Development

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTH2

References

PMID: 12098667 by Hansen I.A., et al. Characterization of the human and mouse genes encoding the tuberoinfundibular peptide of 39 residues, a ligand of the parathyroid hormone receptor family.

PMID: 11818570 by Dobolyi A., et al. Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception.