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- Table of Contents
Facts about Prostaglandin E synthase 3.
Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 into the HSP90 pathway (PubMed:24711448). .
Human | |
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Gene Name: | PTGES3 |
Uniprot: | Q15185 |
Entrez: | 10728 |
Belongs to: |
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p23/wos2 family |
CPGES; cPGESp23; Cytosolic prostaglandin E2 synthase; Hsp90 co-chaperone; p23; P23cytosolic prostaglandin E synthase; Progesterone receptor complex p23; prostaglandin E synthase 3 (cytosolic); prostaglandin E synthase 3; PTGES3; TEBP; TEBPEC 5.3.99.3; Telomerase-binding protein p23; unactive progesterone receptor, 23 kD
Mass (kDA):
18.697 kDA
Human | |
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Location: | 12q13.3|12 |
Sequence: | 12; NC_000012.12 (56663341..56689575, complement) |
Cytoplasm.
PMID: 8114727 by Johnson J.L., et al. Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes.
PMID: 11274138 by Forsythe H.L., et al. Stable association of hsp90 and p23, but Not hsp70, with active human telomerase.