PTGER2 Antibodies

AND PTGER2 ELISA kits, PTGER2 Proteins

Many biological assays use antibodies to detect PTGER2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGER2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGER2 antibodies...

We validate the specificity of these antibodies to PTGER2 by testing them on tissues known to express PTGER2 positively and negatively. Browse below to find the PTGER2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTGER2 Infographic by Boster Bio

All PTGER2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Prostaglandin E Receptor EP2/PTGER2 Antibody Picoband®

1 Q&As

Human

$370
Cat # PB9386
100 μg/vial

Anti-PTGER2 Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M04963
100 μl

Anti-EP2 PTGER2 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A04963-1
100ul

PTGER2 Overview

Facts about Prostaglandin E2 receptor EP2 subtype.

PTGER2 3D structure. Source: alphafold

Prostaglandin E2 receptor EP2 subtype (PTGER2)

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.

The subsequent raise in intracellular cAMP is responsible for the relaxing effect of the receptor on smooth muscle. .

Gene Information

Human
Gene Name:	PTGER2
Uniprot:	P43116
Entrez:	5732

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

EP2; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype; prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E2 receptor EP2 subtype; Prostanoid EP2 receptor; PTGER2

Molecular Weight

Mass (kDA):
39.761 kDA

Genomic Context


Human

Location:	14q22.1
Sequence:	14; NC_000014.9 (52314312..52328598)

Tissue Specificity

Placenta and lung.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Mycoplasma Pneumonia
Inflammation
Neoplasms
Malignant Neoplasms
Carcinoma
Tissue Adhesions
Endometrial Polyp
Carcinogenesis
Tumor Angiogenesis
Lung Neoplasms
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Malignant Squamous Cell Neoplasm

Adenocarcinoma
Malignant Neoplasm Of Lung
Asthma
Colorectal Cancer
Fracture
Neoplasm Metastasis
Pertussis

Pathways

Secretion
Localization
Pathogenesis
Cell Proliferation
Ovulation
Cell Growth
Angiogenesis
Cytokine Production
Fertilization
Immune Response
Parturition
Transport
Cell Death

Inflammatory Response
Luteolysis
Chemotaxis
Cell Migration
Methylation
Phagocytosis
Vasoconstriction

PTMs

Phosphorylation
Methylation
Cleavage
Oxidation
Dephosphorylation

Demethylation
Deacetylation
Decarboxylation
Acetylation
Ubiquitination

Research Areas

Cancer
GPCR
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGER2

References

PMID: 8078484 by Regan J.W., et al. Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.

PMID: 10521663 by Smock S.L., et al. Cloning, structural characterization, and chromosomal localization of the gene encoding the human prostaglandin E2 receptor EP2 subtype.