Ptf1a Antibodies

AND Ptf1a ELISA kits, Ptf1a Proteins

Many biological assays use antibodies to detect Ptf1a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ptf1a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ptf1a antibodies...

We validate the specificity of these antibodies to Ptf1a by testing them on tissues known to express Ptf1a positively and negatively. Browse below to find the Ptf1a antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: Ptgdr

Ptf1a Infographic by Boster Bio

All Ptf1a Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PTF1A Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03891-2
100 μg/vial

Anti-PTF1A Mouse Monoclonal Antibody [Clone ID: OTI1H6]

Human, Mouse, Rat

$523
Cat # M03891
100 µl

PTF1A (NM_178161) Human Over-expression Lysate

Human

$628
Cat # LS256297
100 µg

Ptf1a Overview

Facts about Pancreas transcription factor 1 subunit alpha.

Pancreas transcription factor 1 subunit alpha (Ptf1a)

Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'.

Plays a role in late and early pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue to pancreatic organogenesis or revert back to duodenal fates.

Gene Information

Mouse
Gene Name:	Ptf1a
Uniprot:	Q9QX98
Entrez:	19213

Family

Belongs to:

No superfamily

Alternative Names

bHLH transcription factor p48; BHLHA29; bHLHa29exocrine pancreas-specific transcription factor p48; Class A basic helix-loop-helix protein 29; p48 DNA-binding subunit of transcription factor PTF1; pancreas specific transcription factor, 1a; pancreas transcription factor 1 subunit alpha; Pancreas-specific transcription factor 1a; PTF1A; PTF1P48; PTF1-p48; PTF1-p48class II bHLH protein PTF1A

Molecular Weight

Mass (kDA):
35.185 kDA

Genomic Context


Mouse

Location:	2\|2 A3
Sequence:	2;

Tissue Specificity

Expressed in precursors of pancreatic islets, acini and ducts.

Diseases

Diabetes Mellitus
Congenital Absence
Neoplasms
Hypoplasia
Diabetes Mellitus, Insulin-dependent
Nervousness
Pancreatic Neoplasm
Congenital Abnormality
Pancreatitis
Pancreatic Diseases
Malignant Neoplasms
Congenital Heart Defects

Malignant Neoplasm Of Pancreas
Cell Transformation, Neoplastic
Fetal Growth Retardation
Immunologic Deficiency Syndromes
Ectopic Tissue
Adenocarcinoma
Atrophy

Pathways

Pancreas Development
Cell Differentiation
Neurogenesis
Cell Proliferation
Exocrine Pancreas Development
Pathogenesis
Cell Fate Specification
Cell Cycle
Cell Development
Acinar Cell Differentiation
Transdifferentiation
Gastrulation
Pancreas Morphogenesis

Regeneration
Cell Fate Determination
Liver Development
Cell Cycle Arrest
Regionalization
Mitosis
Neuron Development

PTMs

Acetylation

Methylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ptf1a

References

PMID: 11318877 by Obata J., et al. p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos.

PMID: 11562365 by Rose S.D., et al. The role of PTF1-P48 in pancreatic acinar gene expression.