PTDSS1 Antibodies

AND PTDSS1 ELISA kits, PTDSS1 Proteins

Many biological assays use antibodies to detect PTDSS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTDSS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTDSS1 antibodies...

We validate the specificity of these antibodies to PTDSS1 by testing them on tissues known to express PTDSS1 positively and negatively. Browse below to find the PTDSS1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTDSS1 Infographic by Boster Bio

All PTDSS1 Products

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PTDSS1 (NM_014754) Human Over-expression Lysate

Human

$628
Cat # LS009791
100 µg

PTDSS1 Overview

Facts about Phosphatidylserine synthase 1.

PTDSS1 3D structure. Source: alphafold

Phosphatidylserine synthase 1 (PTDSS1)

Catalyzes a base-exchange reaction where the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine.

Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. .

Gene Information

Human
Gene Name:	PTDSS1
Uniprot:	P48651
Entrez:	9791

Family

Belongs to:

phosphatidyl serine synthase family

Alternative Names

KIAA0024Serine-exchange enzyme I; phosphatidylserine synthase 1; PSS1EC 2.7.8.-; PSSAPSS-1; PtdSer synthase 1

Molecular Weight

Mass (kDA):
55.528 kDA

Genomic Context


Human

Location:	8q22.1
Sequence:	8; NC_000008.11 (96261902..96336995)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Highly enriched in the mitochondria-associated membrane (MAM).

Diseases

Chronic Graft Versus Host Disease
Diabetes Mellitus, Experimental
Graft-vs-host Disease
Diabetes Mellitus

Pathways

Cell Cycle
Insulin Secretion
Pathogenesis
Secretion

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTDSS1

References

PMID: 9539713 by Kuge O., et al. Control of phosphatidylserine biosynthesis through phosphatidylserine-mediated inhibition of phosphatidylserine synthase I in Chinese hamster ovary cells.

PMID: 19014349 by Tomohiro S., et al. Purification and characterization of human phosphatidylserine synthases 1 and 2.