PSMG1 Antibodies

AND PSMG1 ELISA kits, PSMG1 Proteins

Many biological assays use antibodies to detect PSMG1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PSMG1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PSMG1 antibodies...

We validate the specificity of these antibodies to PSMG1 by testing them on tissues known to express PSMG1 positively and negatively. Browse below to find the PSMG1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PSMG1 Infographic by Boster Bio

All PSMG1 Products

Product

Figures

Specificity

Applications

Price

Anti-PSMG1 Antibody

Human

IHC, WB

$405
Cat # A08279
100ul

PSMG1 (NM_003720) Human Recombinant Protein

$1249
Cat # PROTO95456
20 µg

PSMG1 (NM_003720) Human Over-expression Lysate

Human

$628
Cat # LS008624
100 µg

PSMG1 Overview

Facts about Proteasome assembly chaperone 1.

PSMG1 3D structure. Source: alphafold

Proteasome assembly chaperone 1 (PSMG1)

Chaperone protein that promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

Gene Information

Human
Gene Name:	PSMG1
Uniprot:	O95456
Entrez:	8624

Family

Belongs to:

PSMG1 family

Alternative Names

C21-LRP; C21LRPc21-LRP; Chromosome 21 leucine-rich protein; Down syndrome critical region gene 2; DSCR2leucine rich protein C21-LRP; LRPC21; PAC-1; PAC1Down syndrome critical region protein 2; proteasome (prosome, macropain) assembly chaperone 1; proteasome assembling chaperone 1; proteasome assembly chaperone 1

Molecular Weight

Mass (kDA):
32.854 kDA

Genomic Context


Human

Location:	21q22.2
Sequence:	21; NC_000021.9 (39174769..39183514, complement)

Tissue Specificity

In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines.

Subcellular Localizations

Cytoplasm. Endoplasmic reticulum.

Diseases

Down Syndrome
Crohn Disease
Inflammatory Bowel Diseases
Intestinal Diseases
Ulcer
Ulcerative Colitis
Colitis
Trisomy
Endoplasmic Reticulum Stress
Inflammatory Disorder

Tumor Angiogenesis
Colonic Diseases
Neoplasms
Inflammation
Pathologic Neovascularization

Interacting Proteins

PSMG2

Pathways

Pathogenesis
Immune Response
Cell Proliferation
Cell Cycle
Angiogenesis
Localization
Endothelial Cell Proliferation

Autophagy
Embryo Development

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSMG1

References

PMID: 9784380 by Vidal-Taboada J.M., et al. Identification and characterization of a new gene from human chromosome 21 between markers D21S343 and D21S268 encoding a leucine- rich protein.

PMID: 10872820 by Vidal-Taboada J.M., et al. Down syndrome critical region gene 2: expression during mouse development and in human cell lines indicates a function related to cell proliferation.