PSMB5 Antibodies

Proteasome subunit beta type-5 (PSMB5)

Component of the 20S core proteasome complex involved in the proteolytic degradation of the majority of intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles.

Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays an integral role in the maintenance of protein homeostasis by eliminating misfolded or damaged proteins that could impair cellular functions, and by eliminating proteins whose functions are no longer required.

Gene Information

Human
Gene Name:	PSMB5
Uniprot:	P28074
Entrez:	5693

Family

Belongs to:
peptidase T1B family

Alternative Names

LMPXproteasome beta 5 subunit; Macropain epsilon chain; MB1EC 3.4.25.1; Multicatalytic endopeptidase complex epsilon chain; proteasome (prosome, macropain) subunit, beta type, 5; proteasome catalytic subunit 3; Proteasome chain 6; Proteasome epsilon chain; proteasome subunit beta type-5; Proteasome subunit MB1; Proteasome subunit X; proteasome subunit, beta type, 5; PSX large multifunctional protease X; XMGC104214

Molecular Weight

Mass (kDA):
28.48 kDA

Genomic Context

Human
Location:	14q11.2
Sequence:	14; NC_000014.9 (23025851..23035220, complement)

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

• Malignant Neoplasms
• Multiple Myeloma
• Neoplasms
• Neuroblastoma
• Carcinoma
• Malignant Neoplasm Of Breast
• Pituitary Diseases
• Mammary Neoplasms
• Glaucoma
• Arthritis
• Hypokinesia
• Nerve Degeneration
• T Lymphoblastic Leukemia/lymphoma

• Stomach Neoplasms
• Sclerosis
• Primary Lateral Sclerosis
• Clubbing
• Hepatitis B
• Lung Diseases
• Amyotrophic Lateral Sclerosis

Interacting Proteins

• POMP
• PSMB1
• PSMB3
• PSMB7

Pathways

• Cell Death
• Transport
• Cell Cycle
• Cell Proliferation
• Senescence
• Drug Resistance
• Autophagy
• Immune Response
• Proteolysis
• Spermatogenesis
• Cell Cycle Arrest
• Reverse Transcription
• Gene Silencing

• Cellular Senescence
• Replicative Senescence
• Cell Division
• Flight
• Sensitization
• Mrna Transcription
• Embryo Implantation

PTMs

• Phosphorylation
• Ubiquitination

• Cleavage
• Oxidation

Research Areas

• Core ESC-Like Genes
• Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSMB5

Best Uses Of The PSMB5 Marker Antibody From Boster Bio

If you're looking for a PSMB5 marker antibody, you've come to the right place. Boster Bio has high-affinity primary antibodies that are tested for multiple applications. This monoclonal marker antibody for PSMB5 reacts with both mouse and human. You can also use this antibody for IF purposes. We'll be discussing the best uses of PSMB5 markers by Boster Bio in this article.

Boster Bio offers high-affinity primary antibodies

Flow cytometry is a popular research technique, which uses a single antibody to detect a target protein. This technology can be applied on a wide range biological samples such as cells and particles. Boster Bio sells high-affinity, primary antibodies. These products are ideal for many different applications. Boster antibodies, monoclonal or polyclonal in nature, are widely cited because of their high specificity.

Primary antibodies are the active components in immunoassays. They are useful for many different applications, including Western Blotting, immunohistochemistry, histopathology, and proteomics. They can also be used for flow cytometry which measures the number of specific cell types. They can also be used to identify specific cell types in a sample.

Boster has high-affinity prima antibodies

Boster Bio supplies high quality, highly specific, and efficient antibodies to analyze samples by flow cytometry. Flowcytometry is an important technique used in biomedical research. The test involves the analysis and determination of whether a sample is present, usually a cell, or particle. High-affinity primary antibodies from Boster are available as monoclonal or polyclonal antibodies and have been extensively cited.

Primary antibodies are immunoglobulins that bind to a single target antigen. Their quality is determined by their affinity and specificity, which refers to how closely they bind to the antigen of interest. High-affinity primary antibodies will bind to the targeted antigen, while poor-affinity antibodies will bind to unintended antigens. They are useful in detecting, purifying, measuring, and analyzing the antigen of particular interest.