PSIP1 Antibodies

AND PSIP1 ELISA kits, PSIP1 Proteins

Many biological assays use antibodies to detect PSIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PSIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PSIP1 antibodies...

We validate the specificity of these antibodies to PSIP1 by testing them on tissues known to express PSIP1 positively and negatively. Browse below to find the PSIP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PSIP1 Infographic by Boster Bio

All PSIP1 Products

Product

Figures

Specificity

Applications

Price

Anti-LEDGF PSIP1 Monoclonal Antibody

6 Q&As

Human, Monkey, Rat

IF, IHC, WB

$399
Cat # A01960
100μl

PSIP1 PC4 And SFRS1 Interacting Protein 1 Human Recombinant Protein

Human

$960
Cat # PROTO75475
50ug, 100ug, 1mg

Anti-PSIP1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A01960-1
100ul

Anti-PSIP1 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01960-2
100 µg/vial

Anti-PSIP1 / LEDGF Rabbit Monoclonal Antibody

Human

IF, IHC, ICC, WB

$370
Cat # M01960
100 µl/vial

PSIP1 Overview

Facts about PC4 and SFRS1-interacting protein.

PSIP1 3D structure. Source: alphafold

PC4 and SFRS1-interacting protein (PSIP1)

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress reactions.

May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis.

Gene Information

Human
Gene Name:	PSIP1
Uniprot:	O75475
Entrez:	11168

Family

Belongs to:

HDGF family

Alternative Names

CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; DFS70; LEDGF; LEDGFDFS 70; Lens epithelium-derived growth factor; MGC74712; p52; p75; PAIP; PC4 and SFRS1 interacting protein 1; PC4 and SFRS1 interacting protein 2; PC4 and SFRS1-interacting protein; PSIP1; PSIP2; transcriptional coactivator p52/p75; Transcriptional coactivator p75/p52

Molecular Weight

Mass (kDA):
60.103 kDA

Genomic Context


Human

Location:	9p22.3
Sequence:	9; NC_000009.12 (15464066..15511019, complement)

Tissue Specificity

Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

Subcellular Localizations

Nucleus. Remains chromatin-associated throughout the cell cycle.

Diseases

Hiv Infections
Immunologic Deficiency Syndromes
Leukemia
Malignant Neoplasms
Autoimmune Reaction
Myeloid Leukemia
Neoplasms
Autoimmune Diseases
Dermatitis, Atopic
Dermatitis
Leukemia, Myelocytic, Acute
Rheumatism

Autoimmunity
Psoriasis
Anemia
Cell Transformation, Neoplastic
Prostatic Neoplasms
Infective Disorder

Interacting Proteins

RBBP8
SUMO1

Pathways

Dna Integration
Viral Replication
Cell Death
Pathogenesis
Transport
Reverse Transcription
Interphase
Cell Proliferation
Localization
Organ Development
Rna Interference
Secretion
Cell Activation

Photosynthesis
Axon Regeneration
Pigmentation
Regulation Of Gene Expression
Histone Modification
B Cell Activation
Tropism

PTMs

Biotinylation
Phosphorylation

Cleavage
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSIP1

References

PMID: 9822615 by Ge H., et al. Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation.

PMID: 10623627 by Singh D.P., et al. Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts.