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- Table of Contents
Facts about Peroxiredoxin-like 2A.
Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (By similarity). May influence bone resorption and help to maintain bone mass (By similarity).
Mouse | |
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Gene Name: | Prxl2a |
Uniprot: | Q9CYH2 |
Entrez: | 70564 |
Belongs to: |
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peroxiredoxin-like PRXL2 family |
C10orf58; Chromosome 10 Open Reading Frame 58; Family With Sequence Similarity 213, Member A; PAMM; Peroxiredoxin (PRX)-Like 2 Activated In M-CSF Stimulated Monocytes; Peroxiredoxin-Like 2 Activated In M-CSF Stimulated Monocytes; Protein PAMM; Redox-Regulatory Protein PAMM; UPF0765 Protein C10orf58
Mass (kDA):
24.395 kDA
Mouse | |
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Location: | 14|14 B |
Sequence: | 14; |
Expressed in kidney, liver, skin, and brain (PubMed:19951071). Widely expressed with highest levels detected in adipose tissue (PubMed:26438880).
PMID: 19951071 by Xu Y., et al. PAMM: a redox regulatory protein that modulates osteoclast differentiation.
PMID: 26438880 by Guo F., et al. Adipocyte-derived PAMM suppresses macrophage inflammation by inhibiting MAPK signalling.