Neurotrypsin Antibodies

AND PRSS12 ELISA kits, Neurotrypsin Proteins

Many biological assays use antibodies to detect Neurotrypsin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neurotrypsin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neurotrypsin antibodies...

We validate the specificity of these antibodies to Neurotrypsin by testing them on tissues known to express PRSS12 positively and negatively. Browse below to find the PRSS12 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRSS12 Infographic by Boster Bio

All PRSS12 Products

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Product

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Specificity

Applications

Price

Anti-Neurotrypsin PRSS12 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A10045
0.1 mg

Neurotrypsin (PRSS12) (NM_003619) Human Over-expression Lysate

Human

$960
Cat # LS008492
100 µg

PRSS12 Overview

Facts about Neurotrypsin.

PRSS12 3D structure. Source: alphafold

Neurotrypsin (PRSS12)

Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. .

Gene Information

Human
Gene Name:	PRSS12
Uniprot:	P56730
Entrez:	8492

Family

Belongs to:

peptidase S1 family

Alternative Names

brain-specific serine protease 3; BSSP3; BSSP-3; EC 3.4.21; Leydin; MGC12722; Motopsin; MRT1EC 3.4.21.-; neurotrypsin; protease, serine, 12 (neurotrypsin, motopsin); Serine protease 12

Molecular Weight

Mass (kDA):
97.067 kDA

Genomic Context


Human

Location:	4q26
Sequence:	4; NC_000004.12 (118280038..118353042, complement)

Tissue Specificity

Brain and Leydig cells of the testis.

Subcellular Localizations

Secreted.

Diseases

Nervousness
Cell Invasion
Influenza
Anxiety Disorders
Malnutrition
Inflammation

Pathways

Localization
Drug Resistance
Long-term Memory
Glycosylation
Rna Interference

PTMs

Phosphorylation

Glycosylation

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRSS12

References

PMID: 9540828 by Proba K., et al. Cloning and sequencing of the cDNA encoding human neurotrypsin.

PMID: 10103056 by Poorafshar M., et al. Cloning and structural analysis of leydin, a novel human serine protease expressed by the Leydig cells of the testis.