PRRG4 Antibodies

AND PRRG4 ELISA kits, PRRG4 Proteins

Many biological assays use antibodies to detect PRRG4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRRG4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRRG4 antibodies...

We validate the specificity of these antibodies to PRRG4 by testing them on tissues known to express PRRG4 positively and negatively. Browse below to find the PRRG4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRRG4 Infographic by Boster Bio

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PRRG4 (NM_024081) Human Over-expression Lysate

Human

$628
Cat # LS079056
100 µg

PRRG4 Overview

Facts about Transmembrane gamma-carboxyglutamic acid protein 4.

PRRG4 3D structure. Source: alphafold

Transmembrane gamma-carboxyglutamic acid protein 4 (PRRG4)

May control axon guidance throughout the CNS (PubMed:28859078). Prevents the delivery of ROBO1 at the cell surface and downregulates its saying (PubMed:28859078).

Gene Information

Human
Gene Name:	PRRG4
Uniprot:	Q9BZD6
Entrez:	79056

Family

Belongs to:

commissureless family

Alternative Names

proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane); Proline-rich Gla protein 4; TMG4PRGP4Proline-rich gamma-carboxyglutamic acid protein 4; transmembrane gamma-carboxyglutamic acid protein 4

Molecular Weight

Mass (kDA):
25.403 kDA

Genomic Context


Human

Location:	11p13
Sequence:	11; NC_000011.10 (32829756..32858120)

Tissue Specificity

Expressed in lung, liver, kidney, pancreas and placenta.

Subcellular Localizations

Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Colorectal Neoplasms
Colorectal Cancer
Aniridia
Rett Syndrome
Blind Vision
Parkinson Disease
Nephroblastoma
Haploinsufficiency

Autistic Disorder
Neoplasms
Impaired Cognition
Wagr Syndrome

Pathways

Endocytosis
Pathogenesis
Spermatogenesis

PTMs

Cleavage on pair of basic residues
Disulfide bond

Gamma-carboxyglutamic acid
Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRRG4

References

PMID: 11171957 by Kulman J.D., et al. Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissues.

PMID: 28859078 by Justice E.D., et al. The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene.