Proline-rich protein 5 Antibodies

AND PRR5 ELISA kits, Proline-rich protein 5 Proteins

Many biological assays use antibodies to detect Proline-rich protein 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proline-rich protein 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proline-rich protein 5 antibodies...

We validate the specificity of these antibodies to Proline-rich protein 5 by testing them on tissues known to express PRR5 positively and negatively. Browse below to find the PRR5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRR5 Infographic by Boster Bio

All PRR5 Products

Product

Figures

Specificity

Applications

Price

Anti-Proline-rich protein 5 PRR5 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A05975
0.1 mg

Protor 1 (PRR5) (NM_001017529) Human Over-expression Lysate

Human

$628
Cat # LS055615
100 µg

Anti-PRR5 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A05975-1
100 µg/vial

PRR5 Overview

Facts about Proline-rich protein 5.

PRR5 3D structure. Source: alphafold

Proline-rich protein 5 (PRR5)

Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. MTORC2 is activated by growth factors, however, in contrast to mTORC1, seems to be nutrient- insensitive.

MTORC2 appears to work upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. MTORC2 promotes the serum-induced formation of stress-fibers or F-actin.

Gene Information

Human
Gene Name:	PRR5
Uniprot:	P85299
Entrez:	55615

Family

Belongs to:

PROTOR family

Alternative Names

FLJ20185; FLJ20185k; PP610; proline rich 5 (renal); protein observed with Rictor-1; Protor-1; PRR5

Molecular Weight

Mass (kDA):
42.753 kDA

Genomic Context


Human

Location:	22q13.31
Sequence:	22; NC_000022.11 (44668547..44737681)

Tissue Specificity

Most abundant in kidney and liver. Also highly expressed in brain, spleen, testis and placenta. Overexpressed in several colorectal tumors.

Diseases

Cardiac Arrhythmia
Malignant Neoplasms
Carcinogenesis
Neoplasms
Mammary Neoplasms
Physiological Stress
Colorectal Neoplasms
Sclerosis
Malignant Neoplasm Of Breast
Carcinoma
Cardiovascular Diseases
Photophobia

Exhaustion
Colorectal Cancer
Trematode Infections
Cell Invasion
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Diabetes Mellitus

Interacting Proteins

DLG1

Pathways

Cell Growth
Photomorphogenesis
Circadian Rhythm
Cell Proliferation
De-etiolation
Hypersensitivity
Translation
Cold Acclimation
Transport
Tricarboxylic Acid Cycle
Induction Of Apoptosis
Lateral Root Formation
Aging

Proteolysis
Photoperiodism
Localization
Ribosome Biogenesis
Cell Death
Mrna Processing
Freezing Tolerance

PTMs

Phosphorylation

Dephosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRR5

References

PMID: 15718101 by Johnstone C.N., et al. PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas.

PMID: 17461779 by Pearce L.R., et al. Identification of Protor as a novel Rictor-binding component of mTOR complex-2.