PRPF4 Antibodies

AND PRPF4 ELISA kits, PRPF4 Proteins

Many biological assays use antibodies to detect PRPF4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRPF4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRPF4 antibodies...

We validate the specificity of these antibodies to PRPF4 by testing them on tissues known to express PRPF4 positively and negatively. Browse below to find the PRPF4 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRPF4 Infographic by Boster Bio

All PRPF4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PRPF4 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A08225
100ul

PRPF4 (NM_004697) Human Recombinant Protein

$813
Cat # PROTO43172
20 µg

Anti-PRPF4 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M08225
100 μl/vial

Anti-PRPF4 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M08225-1
100 μl/vial

PRPF4 (NM_004697) Human Over-expression Lysate

Human

$628
Cat # LS009128
100 µg

Anti-PRPF4 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A08225-2
100 µg/vial

PRPF4 Overview

Facts about U4/U6 small nuclear ribonucleoprotein Prp4.

PRPF4 3D structure. Source: alphafold

U4/U6 small nuclear ribonucleoprotein Prp4 (PRPF4)

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that's involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). .

Gene Information

Human
Gene Name:	PRPF4
Uniprot:	O43172
Entrez:	9128

Family

Belongs to:

No superfamily

Alternative Names

hPrp4; HPRP4P; HPRP4PRP4/STK/WD splicing factor; PRP4 homolog; PRP4 pre-mRNA processing factor 4 homolog (yeast); Prp4p; PRP4WD splicing factor Prp4; U4/U6 small nuclear ribonucleoprotein Prp4; U4/U6 snRNP 60 kDa protein

Molecular Weight

Mass (kDA):
58.449 kDA

Genomic Context


Human

Location:	9q32
Sequence:	9; NC_000009.12 (113275634..113292905)

Subcellular Localizations

Nucleus. Nucleus speckle.

Diseases

Retinitis Pigmentosa
Malignant Neoplasms
Brain Ischemia
Retinal Degeneration
Adult Acute Myeloblastic Leukemia
Malignant Neoplasm Of Breast
Infectious Mononucleosis
Hypoxia
Aneuploidy
Blind Vision
Brain Hypoxia
Leukemia, Myelocytic, Acute

Haploinsufficiency
Disorder Of Eye
Myeloid Leukemia
Leukemia
Eye Diseases, Hereditary
Malignant Neoplasm Of Ovary

Interacting Proteins

GPKOW
PPIH

Pathways

Mitosis
Circadian Rhythm
Localization
Anaphase
Rna Splicing
Cell Division
Drug Resistance
Spindle Checkpoint
Regulation Of Mitosis
Protein Folding

Spindle Assembly Checkpoint
Rna Processing
Regulation Of Cell Division
Rna Interference
Spindle Assembly

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRPF4

References

PMID: 9257651 by Lauber J., et al. The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p.

PMID: 9404889 by Horowitz D.S., et al. A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs.