PRPF3 Antibodies

AND PRPF3 ELISA kits, PRPF3 Proteins

Many biological assays use antibodies to detect PRPF3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRPF3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRPF3 antibodies...

We validate the specificity of these antibodies to PRPF3 by testing them on tissues known to express PRPF3 positively and negatively. Browse below to find the PRPF3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRPF3 Infographic by Boster Bio

All PRPF3 Products

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Product

Figures

Specificity

Applications

Price

Anti-PRPF3 Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A05255
100ul

PRPF3 (NM_004698) Human Over-expression Lysate

Human

$628
Cat # LS009129
100 µg

PRPF3 Overview

Facts about U4/U6 small nuclear ribonucleoprotein Prp3.

PRPF3 3D structure. Source: alphafold

U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3)

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). .

Gene Information

Human
Gene Name:	PRPF3
Uniprot:	O43395
Entrez:	9129

Family

Belongs to:

No superfamily

Alternative Names

hPrp3; HPRP3P; HPRP3retinitis pigmentosa 18 (autosomal dominant); Pre-mRNA-splicing factor 3; PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae); PRP3 pre-mRNA processing factor 3 homolog (yeast); PRP3; Prp3p; RP18; U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor

Molecular Weight

Mass (kDA):
77.529 kDA

Genomic Context


Human

Location:	1q21.2
Sequence:	1; NC_000001.11 (150321468..150353233)

Tissue Specificity

Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain.

Subcellular Localizations

Nucleus. Nucleus speckle.

Diseases

Retinitis Pigmentosa
Retinal Degeneration
Night Blindness
Blind Vision
Retinal Diseases
Hereditary Diseases
Retinal Dystrophies
Brain Ischemia
Infectious Mononucleosis
Stargardt's Disease
Hypoxia

De Novo Mutation
Vitelliform Macular Dystrophy
Carcinoma
Brain Hypoxia
Chimera Disorder

Interacting Proteins

DVL3
FAM9B
GPRASP2
MFAP1
NKAP

PSMD3
SF3B2
SLU7
SMNDC1
TRIM39

U2AF2

Pathways

Rna Splicing
Rna Processing
Pathogenesis
Mrna Splicing
Cell Death
Localization
Circadian Rhythm
Cell Cycle
Protein Folding

Mrna Processing
Receptor Recycling
Liver Development

PTMs

Phosphorylation

Methylation

Ubiquitination

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRPF3

References

PMID: 9328476 by Wang A., et al. Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome.

PMID: 9404889 by Horowitz D.S., et al. A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs.