Prokineticin receptor 2 Antibodies

AND PROKR2 ELISA kits, Prokineticin receptor 2 Proteins

Many biological assays use antibodies to detect Prokineticin receptor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prokineticin receptor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prokineticin receptor 2 antibodies...

We validate the specificity of these antibodies to Prokineticin receptor 2 by testing them on tissues known to express PROKR2 positively and negatively. Browse below to find the PROKR2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PROKR2 Infographic by Boster Bio

All PROKR2 Products

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Specificity

Applications

Price

Anti-PKR2 PROKR2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A03340
100ul

GPR73B (PROKR2) (NM_144773) Human Over-expression Lysate

Human

$628
Cat # LS128674
100 µg

PROKR2 Overview

Facts about Prokineticin receptor 2.

PROKR2 3D structure. Source: alphafold

Prokineticin receptor 2 (PROKR2)

Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins.

Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. .

Gene Information

Human
Gene Name:	PROKR2
Uniprot:	Q8NFJ6
Entrez:	128674

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

dJ680N4.3; G protein-coupled receptor 73-like 1; GPR73bG-protein coupled receptor 73-like 1; GPR73L1; GPR73L1Kallmann syndrome 3 (autosomal dominant); GPRg2; GPRg2KAL3; KAL3; PKR2; PKR2PK-R2; Prokineticin R2; prokineticin receptor 2; ProkineticinR2; PROKR2

Molecular Weight

Mass (kDA):
43.996 kDA

Genomic Context


Human

Location:	20p12.3
Sequence:	20; NC_000020.11 (5298852..5316732, complement)

Tissue Specificity

Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hypogonadism
Kallmann Syndrome
Hypogonadotropic Hypogonadism
Anosmia
Idiopathic Hypogonadotropic Hypogonadism
Tumor Angiogenesis
Olfaction Disorders
Pituitary Diseases
Hereditary Diseases
Hypoplasia
Malignant Neoplasms
Congenital Absence

Charge Syndrome
Pain
Amenorrhea
Cryptorchidism
Hypoxia
Infertility
Major Depressive Disorder

Pathways

Secretion
Angiogenesis
Pathogenesis
Neurogenesis
Localization
Immune Response
Circadian Rhythm
Transport
Spermatogenesis
Sensitization
Monocyte Activation
Neuron Migration
Cell Adhesion

Reproductive System Development
Chemokine Production
Regulation Of Behavior
Muscle Contraction
Sex Determination
Cell Fate Specification
Inflammatory Response

PTMs

Disulfide bond

Glycoprotein

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PROKR2

References

PMID: 11886876 by Lin D.C.-H., et al. Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor.

PMID: 12427552 by Soga T., et al. Molecular cloning and characterization of prokineticin receptors.