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Protamine-2 Antibodies

AND PRM2 ELISA kits, Protamine-2 Proteins

Many biological assays use antibodies to detect Protamine-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protamine-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protamine-2 antibodies...

We validate the specificity of these antibodies to Protamine-2 by testing them on tissues known to express PRM2 positively and negatively. Browse below to find the PRM2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRM2 Infographic by Boster Bio

PRM2 protein infographic

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Protamine 2 (PRM2) (NM_002762) Human Over-expression Lysate

Human

$628
Cat # LS005620
100 µg

PRM2 Overview

Facts about Protamine-2.

PRM2 3D structure

PRM2 3D structure. Source: alphafold

Protamine-2 (PRM2)

Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

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Gene Information

Human
Gene Name:	PRM2
Uniprot:	P04554
Entrez:	5620

Gene Information

Family

Belongs to:

protamine P2 family

Family

Alternative Names

cancer/testis antigen family 94, member 2; CT94.2; FLJ27447; protamine 2; protamine-2; Sperm histone P2; Sperm protamine P2

Molecular Weight

Mass (kDA):
13.051 kDA

Molecular Weight

Genomic Context


Human

Location:	16p13.13
Sequence:	16; NC_000016.10 (11275639..11276480, complement)

Tissue Specificity

Testis.

Subcellular Localizations

Nucleus. Chromosome.

Subcellular Localization

Diseases

Infertility
Male Infertility
Azoospermia
Oligospermia
Haploinsufficiency
Sterility
Chimera Disorder
Acute Erythroblastic Leukemia
Hemolysis (disorder)
Cardiovascular Diseases

Pituitary Diseases
Embryonic Mosaic
Dysequilibrium Syndrome
Infective Disorder

Disease

Pathways

Spermatogenesis
Translation
Fertilization
Reverse Transcription
Localization
Embryo Development
Sperm Motility
Pachytene
Regulation Of Gene Expression
Chromatin Remodeling
Cell Development
Spermatid Differentiation
Methylation

Germ Cell Development
Acrosome Reaction
Secretion
Response To Pheromone
Aging
Histone Modification
Cytokinesis

Pathways

PTMs

Demethylation

Acetylation

Methylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRM2

References

PMID: 3412906 by Domenjoud L., et al. Sequence of human protamine 2 cDNA.

PMID: 2081589 by Domenjoud L., et al. Genomic sequences of human protamines whose genes, PRM1 and PRM2, are clustered.