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- Table of Contents
Facts about Proline dehydrogenase 1, mitochondrial.
Human | |
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Gene Name: | PRODH |
Uniprot: | O43272 |
Entrez: | 5625 |
Belongs to: |
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proline oxidase family |
EC 1.5.99.8; FLJ33744; HSPOX2; mitochondrial; p53-induced gene 6 protein; PIG6MGC148078; POX2; PRODH2MGC148079; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase ); Proline oxidase; proline oxidase, mitochondrial; SCZD4; tumor protein p53 inducible protein 6
Mass (kDA):
68.002 kDA
Human | |
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Location: | 22q11.21 |
Sequence: | 22; NC_000022.11 (18912781..18936553, complement) |
Expressed in lung, skeletal muscle and brain, to a lesser extent in heart and kidney, and weakly in liver, placenta and pancreas.
Mitochondrion matrix.
PMID: 9385373 by Campbell H.D., et al. A human homologue of the Drosophila melanogaster sluggish-A (proline oxidase) gene maps to 22q11.2, and is a candidate gene for type-I hyperprolinaemia.
PMID: 10192398 by Gogos J.A., et al. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice.