PRKRA Antibodies

AND PRKRA ELISA kits, PRKRA Proteins

Many biological assays use antibodies to detect PRKRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKRA antibodies...

We validate the specificity of these antibodies to PRKRA by testing them on tissues known to express PRKRA positively and negatively. Browse below to find the PRKRA antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRKRA Infographic by Boster Bio

All PRKRA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PRKRA Antibody

Mouse

IHC, WB

$405
Cat # A02744
100ul

Human PACT Recombinant Protein

SDS-PAGE

$265
Cat # PROTO75569
Starting from 10ug

Anti-PRKRA Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M02744
100 μl/vial

Anti-PRKRA Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02744-2
100 μg/vial

PRKRA (NM_003690) Human Over-expression Lysate

Human

$628
Cat # LS008575
100 µg

PRKRA Overview

Facts about Interferon-inducible double-stranded RNA-dependent protein kinase activator A.

PRKRA 3D structure. Source: alphafold

Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA)

Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), resulting in phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for following siRNA-mediated post- transcriptional gene silencing.

Doesn't seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at'Lys-386' in'Ser-392' respectively and enhances its activity at a EIF2AK2/PKR-dependent manner (By similarity).

Gene Information

Human
Gene Name:	PRKRA
Uniprot:	O75569
Entrez:	8575

Family

Belongs to:

PRKRA family

Alternative Names

DYT16; DYT16interferon-inducible double stranded RNA-dependent activator; HSD14; PACT; PACTPKR-associating protein X; PKR-associated protein X; PKR-Associating Protein X; PRKRA; protein kinase, interferon-inducible double stranded RNA dependent activator; RAX; RAXHSD14