PRKCSH Antibodies

AND PRKCSH ELISA kits, PRKCSH Proteins

Many biological assays use antibodies to detect PRKCSH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKCSH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKCSH antibodies...

We validate the specificity of these antibodies to PRKCSH by testing them on tissues known to express PRKCSH positively and negatively. Browse below to find the PRKCSH antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRKCSH Infographic by Boster Bio

All PRKCSH Products

Product

Figures

Specificity

Applications

Price

Anti-GLU2B PRKCSH Antibody

13 Q&As

Human, Mouse

IF, WB

$360
Cat # A04992
100 µl

Anti-Glucosidase II Beta (K117) PRKCSH Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A04992-1
100ul

Anti-GLU2B Rabbit Monoclonal Antibody

Human

IF, IHC, ICC, WB

$370
Cat # M04992
100 μl/vial

Glucosidase 2 subunit beta (PRKCSH) (NM_002743) Human Over-expression Lysate

Human

$960
Cat # LS005589
100 µg

Anti-PRKCSH Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A04992-2
100 µg/vial

PRKCSH Overview

Facts about Glucosidase 2 subunit beta.

PRKCSH 3D structure. Source: alphafold

Glucosidase 2 subunit beta (PRKCSH)

Regulatory subunit of glucosidase II which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity).

Gene Information

Human
Gene Name:	PRKCSH
Uniprot:	P14314
Entrez:	5589

Family

Belongs to:

No superfamily

Alternative Names

AGE-R2,80K-H protein; G19P1AGE-binding receptor 2; glucosidase 2 subunit beta; Glucosidase II subunit beta; glucosidase II, beta subunit; hepatocystin; PCLD; PKCSH; PLD1; Protein kinase C substrate 60.1 kDa protein heavy chain; protein kinase C substrate 80K-H; protein kinase C substrate, 80 Kda protein

Molecular Weight

Mass (kDA):
59.425 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (11435257..11450968)

Subcellular Localizations

Endoplasmic reticulum.

Diseases

Liver Diseases
Polycystic Liver Disease
Polycystic Kidney, Autosomal Dominant
Polycystic Kidney Diseases
Kidney Diseases
Hepatic Cyst
Cystic Disease -retired-
Carcinoma
Fenestration (morphologic Abnormality)
Bipolar Disorder
Tissue Adhesions
Autosomal Recessive Polycystic Kidney Disease

Caroli Disease
Neoplasms
Hypertension, Portal
Germline Mutation Abnormality
Neuroblastoma
Liver Failure
Hypertensive Disease

Pathways

Localization
Transport
Cell Proliferation
Protein Phosphorylation
Aging
Proteolysis
Translation
Glycosylation
Cell Growth
Pathogenesis
Secretion
Cell Adhesion
Myoblast Migration

Cell Migration
Electron Transport
Electron Transport Chain
Fertilization
Regulation Of Gene Expression
Regulation Of Autophagy
Membrane Depolarization

PTMs

Phosphorylation
Myristoylation
Glycosylation

Cleavage
Oxidation
Ubiquitination

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKCSH

References

PMID: 2793184 by Sakai K., et al. Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein.

PMID: 9043864 by Ophoff R.A., et al. A 3-Mb region for the familial hemiplegic migraine locus on 19p13.1- p13.2: exclusion of PRKCSH as a candidate gene.