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- Table of Contents
2 Citations
3 Citations 6 Q&As
Facts about Protein kinase C gamma type.
May be involved in the regulation of hippocampal long-term potentiation (LTP), but might be not essential for the practice of synaptic plasticity. May be involved in desensitization of mu-type opioid receptor-mediated G-protein activation in the spinal cord, and might be crucial for the development and/or maintenance of morphine-induced reinforcing consequences in the limbic forebrain.
Human | |
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Gene Name: | PRKCG |
Uniprot: | P05129 |
Entrez: | 5582 |
Belongs to: |
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protein kinase superfamily |
EC 2.7.11; EC 2.7.11.13; MGC57564; PKC gamma; PKCC; PKCCSCA14; PKCG; PKC-gamma; PKCGprotein kinase C gamma type; PRKCG; protein kinase C, gamma; SCA14
Mass (kDA):
78.448 kDA
Human | |
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Location: | 19q13.42 |
Sequence: | 19; NC_000019.10 (53882197..53907652) |
Expressed in Purkinje cells of the cerebellar cortex.
Cytoplasm. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein. Cell junction, synapse, synaptosome. Cell projection, dendrite. Translocates to synaptic membranes on stimulation.
PMID: 3755548 by Coussens L., et al. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.
PMID: 8375396 by Kochs G., et al. Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes.
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