PRKAG2 Antibodies

AND PRKAG2 ELISA kits, PRKAG2 Proteins

Many biological assays use antibodies to detect PRKAG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKAG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKAG2 antibodies...

We validate the specificity of these antibodies to PRKAG2 by testing them on tissues known to express PRKAG2 positively and negatively. Browse below to find the PRKAG2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRKAG2 Infographic by Boster Bio

All PRKAG2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PRKAG2 Antibody

1 Q&As

Human

IF, IHC, WB

$360
Cat # A02758
100 µl

Anti-AMPK gamma2 PRKAG2 Antibody

6 Q&As

Human, Mouse

$399
Cat # A02758-1
100μl

Anti-AMP gamma PRKAG2 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A02758-2
100ul

Anti-PRKAG2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A02758-3
100 μg/vial

PRKAG2 (NM_016203) Human Over-expression Lysate

Human

$960
Cat # LS051422
100 µg

PRKAG2 Overview

Facts about 5'-AMP-activated protein kinase subunit gamma-2.

PRKAG2 3D structure. Source: alphafold

5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2)

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.

AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.

Gene Information

Human
Gene Name:	PRKAG2
Uniprot:	Q9UGJ0
Entrez:	51422

Family

Belongs to:

5'-AMP-activated protein kinase gamma subunit family

Alternative Names

AAKG; AAKG2; CMH6AMPK subunit gamma-2; H91620pAMPK gamma2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; WPWS5'-AMP-activated protein kinase subunit gamma-2

Molecular Weight

Mass (kDA):
63.066 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (151556114..151877115, complement)

Tissue Specificity

Isoform B is ubiquitously expressed except in liver and thymus. The highest level is detected in heart with abundant expression in placenta and testis.

Diseases

Hypertrophy
Cardiomyopathies
Hypertrophic Cardiomyopathy
Wolff-parkinson-white Syndrome
Cardiac Hypertrophy
Left Ventricular Hypertrophy
Glycogen Storage Disease
Cardiac Arrhythmia
Pre-excitation Syndromes
Danon Disease
Heart Diseases
Cardiomyopathy, Hypertrophic, Familial

Sudden Cardiac Death
Storage Disease
Sudden Death
Cardiac Death
Cardiac Fibrillation
Atrial Fibrillation

Pathways

Pathogenesis
Energy Homeostasis
Cardiac Conduction
Transport
Glomerular Filtration
Fatty Acid Oxidation
Glycolysis
Aging
Response To Metformin
Localization

Cell Cycle
Angiogenesis
Lipid Storage
Glucose Transport
Secretion

PTMs

Phosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKAG2

References

PMID: 10698692 by Cheung P.C.F., et al. Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.

PMID: 11112354 by Lang T.M., et al. Molecular cloning, genomic organization, and mapping of PRKAG2, a heart abundant gamma-2 subunit of 5'-AMP-activated protein kinase, to human chromosome 7q36.