PREX2 Antibodies

AND PREX2 ELISA kits, PREX2 Proteins

Many biological assays use antibodies to detect PREX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PREX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PREX2 antibodies...

We validate the specificity of these antibodies to PREX2 by testing them on tissues known to express PREX2 positively and negatively. Browse below to find the PREX2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PREX2 Infographic by Boster Bio

All PREX2 Products

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Product

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Specificity

Applications

Price

PREX2 (NM_024870) Human Over-expression Lysate

Human

$960
Cat # LS080243
100 µg

Anti-PREX2 Antibody Picoband®

Human, Mouse

ELISA, WB

$370
Cat # A06715-1
100 µg/vial

PREX2 Overview

Facts about Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein.

PREX2 3D structure. Source: alphafold

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2)

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its action is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein.

Mediates the activation of RAC1 at a PI3K-dependent Method. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase.

Gene Information

Human
Gene Name:	PREX2
Uniprot:	Q70Z35
Entrez:	80243

Family

Belongs to:

No superfamily

Alternative Names

DEP domain-containing protein 2; DEP.2; DEPDC2; phosphatidylinositol 34,5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol-34,5-trisphosphate-dependent Rac exchange factor 2; P-REX2,6230420N16Rik; PtdIns(34,5)-dependent Rac exchanger 2

Molecular Weight

Mass (kDA):
182.622 kDA

Genomic Context


Human

Location:	8q13.2
Sequence:	8; NC_000008.11 (67951918..68237032)

Tissue Specificity

Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.