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- Table of Contents
Facts about Thioredoxin-dependent peroxide reductase, mitochondrial.
Acts synergistically with MAP3K13 to modulate the activation of NF-kappa-B from the cytosol (PubMed:12492477). .
Human | |
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Gene Name: | PRDX3 |
Uniprot: | P30048 |
Entrez: | 10935 |
Belongs to: |
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peroxiredoxin family |
Antioxidant protein 1MGC104387; AOP-1; AOP-1MGC24293; AOP1PRO1748; EC 1.11.1.15; HBC189; MER5; Peroxiredoxin 3; Peroxiredoxin III; peroxiredoxin-3; PRDX3; Protein MER5 homolog; prx-III; SP-22; thioredoxin-dependent peroxide reductase, mitochondrial
Mass (kDA):
27.693 kDA
Human | |
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Location: | 10q26.11 |
Sequence: | 10; NC_000010.11 (119167720..119178812, complement) |
Mitochondrion. Cytoplasm. Early endosome. Localizes to early endosomes in a RPS6KC1-dependent manner.
PMID: 7733872 by Tsuji K., et al. Mammalian antioxidant protein complements alkylhydroperoxide reductase (ahpC) mutation in Escherichia coli.
PMID: 1286669 by Hochstrasser D.F., et al. Human liver protein map: a reference database established by microsequencing and gel comparison.