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Peroxiredoxin-1 Antibodies
AND PRDX1 ELISA kits, Peroxiredoxin-1 Proteins
Many biological assays use antibodies to detect Peroxiredoxin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Peroxiredoxin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Peroxiredoxin-1 antibodies...
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PRDX1 Infographic by Boster Bio
All PRDX1 Products
Product
Figures
Specificity
Applications
Price
Anti-Peroxiredoxin 1/PRDX1 Antibody Picoband®
1 Citations 1 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9348
100 μg/vial
Cat # PB9348
100 μg/vial
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01845
100 μl
Cat # M01845
100 μl
Enzyme Activity, SDS-PAGE
$275
Cat # PROTP35700
Starting from 10ug
Cat # PROTP35700
Starting from 10ug
PRDX1 Overview
Facts about Peroxiredoxin-1.
Peroxiredoxin-1 (PRDX1)
Thiol-specific peroxidase which catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Might take part in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the capability to GDPD5 to induce postmitotic motor neuron differentiation (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | PRDX1 |
| Uniprot: | Q06830 |
| Entrez: | 5052 |
Family
| Belongs to: |
|---|
| peroxiredoxin family |
Alternative Names
EC 1.11.1; EC 1.11.1.15; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NKEFA; NKEF-A; PAG; PAGAMSP23; PAGB; Peroxiredoxin 1; peroxiredoxin-1; PRDX1; proliferation-associated gene A; Proliferation-associated gene protein; PRX1; PRXI; TDPX2; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2
Molecular Weight
Mass (kDA):
22.11 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.1 |
| Sequence: | 1; NC_000001.11 (45511035..45522890, complement) |
Subcellular Localizations
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Lung Neoplasms
- Adenocarcinoma
- Carcinogenesis
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Lung
- Inflammation
- Diabetes Mellitus
- Malignant Paraganglionic Neoplasm
- Malignant Squamous Cell Neoplasm
- Neoplasm Metastasis
Interacting Proteins
- AR
- PRNP
- PTEN
- SRXN1
- STK4
- TERF1
- TPT1
Pathways
- Cell Death
- Cell Proliferation
- Pathogenesis
- Response To Oxidative Stress
- Localization
- Cell Differentiation
- Cell Cycle
- Translation
- Neuroprotection
- Cell Migration
- Embryo Development
- Oocyte Maturation
- Transport
PTMs
- Oxidation
- Phosphorylation
- Reduction
- Acetylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRDX1
bosterbio.com/bosterbio-gene-info-cards/PRDX1
References
PMID: 8496166 by Prosperi M.T., et al. A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins.
PMID: 8026862 by Shau H., et al. Cloning and sequence analysis of candidate human natural killer- enhancing factor genes.
1 Publications of Boster Peroxiredoxin-1 Antibodies & ELISA Kits
- PubMed ID: 10.3389/fnins.2020.00181, Prdx1 Reduces Intracerebral Hemorrhage-Induced Brain Injury via Targeting Inflam...
*More publications can be found for each product on its corresponding product page