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- Table of Contents
Facts about PR domain zinc finger protein 8.
Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it's necessary for rod bipolar and form 2 OFF-cone bipolar cell survival (By similarity).
Human | |
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Gene Name: | PRDM8 |
Uniprot: | Q9NQV8 |
Entrez: | 56978 |
Belongs to: |
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class V-like SAM-binding methyltransferase superfamily |
PFM5; PR domain containing 8; PR domain zinc finger protein 8; PR domain-containing protein 8; PR-domain containing protein 8
Mass (kDA):
71.663 kDA
Human | |
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Location: | 4q21.21 |
Sequence: | 4; NC_000004.12 (80183418..80204329) |
Expressed in brain, heart, skeletal muscle, testes, prostate.
Nucleus.
PMID: 22961547 by Turnbull J., et al. Early-onset Lafora body disease.