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- Table of Contents
Facts about PR domain-containing protein 11.
Human | |
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Gene Name: | PRDM11 |
Uniprot: | Q9NQV5 |
Entrez: | 56981 |
Belongs to: |
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class V-like SAM-binding methyltransferase superfamily |
PFM8PR domain-containing protein 11; PR domain containing 11; PR-domain containing protein 11
Mass (kDA):
57.863 kDA
Human | |
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Location: | 11p11.2 |
Sequence: | 11; NC_000011.10 (45094013..45235124) |
Highly expressed in lung, including bronchial epithelial cells and airway smooth muscle cells, as well as in peripheral blood mononuclear cells. In tonsils, expressed in B- cell types, including naive B-cells, centroblasts, centrocytes and memory B-cells (at protein level). In benign hyperplastic lymph nodes, expressed in germinal center cells in both the dark and light zones, as well as in scattered cells in the mantle zone and the interfollicular area (at protein level).
Nucleus. Cytoplasm.
PMID: 24929828 by Loth D.W., et al. Genome-wide association analysis identifies six new loci associated with forced vital capacity.
PMID: 25499759 by Fog C.K., et al. Loss of PRDM11 promotes MYC-driven lymphomagenesis.