This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Serine/threonine-protein phosphatase 6 regulatory subunit 2.
Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. .
Human | |
---|---|
Gene Name: | PPP6R2 |
Uniprot: | O75170 |
Entrez: | 9701 |
Belongs to: |
---|
SAPS family |
dJ579N16.1; KIAA0685PP6R2SAPS2serine/threonine-protein phosphatase 6 regulatory subunit 2; protein phosphatase 6, regulatory subunit 2; SAP190; SAPS domain family member 2; SAPS domain family, member 2
Mass (kDA):
104.942 kDA
Human | |
---|---|
Location: | 22q13.33 |
Sequence: | 22; NC_000022.11 (50343327..50445090) |
Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta.
Cytoplasm.
PMID: 16769727 by Stefansson B., et al. Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon.
PMID: 18186651 by Stefansson B., et al. Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.