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- Table of Contents
Facts about Centrosomal protein of 57 kDa.
Mediates nuclear translocation and mitogenic action of the internalized growth factor FGF2, but that of FGF1. .
Human | |
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Gene Name: | CEP57 |
Uniprot: | Q86XR8 |
Entrez: | 9702 |
Belongs to: |
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translokin family |
centrosomal protein 57kDa; Cep57; FGF2-interacting protein; KIAA0092centrosomal protein of 57 kDa; PIG8; Testis-specific protein 57; Translokin; TSP57proliferation-inducing protein 8
Mass (kDA):
57.089 kDA
Human | |
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Location: | 11q21 |
Sequence: | 11; NC_000011.10 (95790461..95832693) |
Ubiquitous.
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
PMID: 12717444 by Bossard C., et al. Translokin is an intracellular mediator of FGF-2 trafficking.
PMID: 21552266 by Snape K., et al. Mutations in CEP57 cause mosaic variegated aneuploidy syndrome.