PPP1R3B Antibodies

AND PPP1R3B ELISA kits, PPP1R3B Proteins

Many biological assays use antibodies to detect PPP1R3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP1R3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP1R3B antibodies...

We validate the specificity of these antibodies to PPP1R3B by testing them on tissues known to express PPP1R3B positively and negatively. Browse below to find the PPP1R3B antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP1R3B Infographic by Boster Bio

All PPP1R3B Products

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Product

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Specificity

Applications

Price

Human PPP1R3B Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ86XI6
Starting from 20ug

PPP1R3B (NM_024607) Human Over-expression Lysate

Human

$628
Cat # LS079660
100 µg

Anti-PPP1R3B Antibody Picoband®

Human

ELISA, WB

$370
Cat # A09697
100 µg/vial

PPP1R3B Overview

Facts about Protein phosphatase 1 regulatory subunit 3B.

PPP1R3B 3D structure. Source: alphafold

Protein phosphatase 1 regulatory subunit 3B (PPP1R3B)

Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity.

Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and so limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1.

Gene Information

Human
Gene Name:	PPP1R3B
Uniprot:	Q86XI6
Entrez:	79660

Family

Belongs to:

No superfamily

Alternative Names

FLJ14005; FLJ34675; GL; Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL; PPP1R4PP1 subunit R4; protein phosphatase 1 regulatory subunit 3B; Protein phosphatase 1 regulatory subunit 4; Protein phosphatase 1 subunit GL; protein phosphatase 1, regulatory (inhibitor) subunit 3B

Molecular Weight

Mass (kDA):
32.695 kDA

Genomic Context


Human

Location:	8p23.1
Sequence:	8; NC_000008.11 (9136255..9151586, complement)

Tissue Specificity

Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level). Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart. Weak expression in placenta and lung.

Diseases

Diabetes Mellitus
Coronary Artery Disease
Diabetes Mellitus, Non-insulin-dependent
Liver Diseases
Inflammation
Stomach Neoplasms
Coronary Heart Disease
Colonic Neoplasms
Nonalcoholic Fatty Liver Disease
Myocardial Infarction
Cardiovascular Diseases
Malignant Neoplasms
Neoplasms

Maturity Onset Diabetes Mellitus In Young
Fatty Liver
Severe Myopia
Chronic Inflammation
Steatohepatitis
Retinal Detachment
Steatosis

Interacting Proteins

PPP1CA

Pathways

Transport
Protein Targeting
Glucose Homeostasis
Cell Cycle
Lung Development
Immune Response
Muscle Contraction

Glucose Transport

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP1R3B

References

PMID: 11872655 by Munro S., et al. Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver.

PMID: 17555403 by Montori-Grau M., et al. Expression and glycogenic effect of glycogen-targeting protein phosphatase 1 regulatory subunit GL in cultured human muscle.