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- Table of Contents
Facts about Protein phosphatase 1 regulatory subunit 3A.
Seems to act as a glycogen-targeting subunit for PP1.
PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.Plays an important role in glycogen synthesis but isn't essential for insulin activation of glycogen synthase (By similarity). .
Human | |
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Gene Name: | PPP1R3A |
Uniprot: | Q16821 |
Entrez: | 5506 |
Belongs to: |
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No superfamily |
glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle; GM; PP1G; PPP1R3; protein phosphatase 1 glycogen- associated regulatory subunit; Protein phosphatase 1 glycogen-associated regulatory subunit; protein phosphatase 1 regulatory subunit 3A; protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen andsarcoplasmic reticulum binding subunit, skeletal muscle); protein phosphatase 1, regulatory (inhibitor) subunit 3A; Protein phosphatase type-1 glycogen targeting subunit; RG1; serine /threonine specific protein phosphatase; type-1 protein phosphatase skeletal muscle glyco
Mass (kDA):
125.767 kDA
Human | |
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Location: | 7q31.1 |
Sequence: | 7; NC_000007.14 (113876777..113919094, complement) |
Skeletal muscle and heart.
Membrane; Single-pass membrane protein.
PMID: 9726244 by Xia J., et al. A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes.
PMID: 7926294 by Chen Y.H., et al. Sequence of the human glycogen-associated regulatory subunit of type I protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with non-insulin-dependent diabetes.