PPP1R3C Antibodies

AND PPP1R3C ELISA kits, PPP1R3C Proteins

Many biological assays use antibodies to detect PPP1R3C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP1R3C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP1R3C antibodies...

We validate the specificity of these antibodies to PPP1R3C by testing them on tissues known to express PPP1R3C positively and negatively. Browse below to find the PPP1R3C antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP1R3C Infographic by Boster Bio

All PPP1R3C Products

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Specificity

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Anti-PPP1R3C Antibody

1 Q&As

Human, Monkey

ELISA, IHC-P, WB, IF (paraffin)

$335
Cat # A06658
100ul

Anti-PTG PPP1R3C Antibody

Human, Monkey

ELISA, IHC, WB

$380
Cat # A06658-1
100ul

PPP1R3C (NM_005398) Human Over-expression Lysate

Human

$628
Cat # LS005507
100 µg

PPP1R3C Overview

Facts about Protein phosphatase 1 regulatory subunit 3C.

PPP1R3C 3D structure. Source: alphafold

Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)

Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.

Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a number of cell types. .

Gene Information

Human
Gene Name:	PPP1R3C
Uniprot:	Q9UQK1
Entrez:	5507

Family

Belongs to:

No superfamily

Alternative Names

Phosphatase 1, regulatory inhibitor subunit 5; PPP1R5PP1 subunit R5; protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; Protein targeting to glycogen; PTG

Molecular Weight

Mass (kDA):
36.445 kDA

Genomic Context


Human

Location:	10q23.32
Sequence:	10; NC_000010.11 (91628442..91633071, complement)

Diseases

Myoclonus
Myoclonic Epilepsies, Progressive
Epilepsy
Epilepsies, Myoclonic
Lafora Disease
Insulin Resistance
Impaired Glucose Tolerance
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Neurodegenerative Disorders
Malignant Neoplasms
Nervousness

Liver Carcinoma
Eyelid Diseases
Tongue Neoplasms
Coronary Heart Disease
Melanoma
Colonic Neoplasms
Glioma

Interacting Proteins

EPM2A
GYS1
PPP1CA
PPP1CB
PPP1CC

Pathways

Protein Targeting
Transport
Keratinization
Aging
Dna Methylation
Keratinocyte Differentiation
Localization
Cell Cycle Arrest
Methylation
Glucose Homeostasis
Dna Replication
Chemotaxis

Cell Death
Cell Cycle
Extracellular Matrix Organization
Response To Hydrogen Peroxide
Glucose Transport
Cellular Response To Hydrogen Peroxide

PTMs

Phosphorylation
Dephosphorylation

Ubiquitination
Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP1R3C

References

PMID: 8985175 by Doherty M.J., et al. Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1.

PMID: 10222257 by Permana P.A., et al. Protein targeting to glycogen/PPP1R5: screening of coding and flanking genomic regions for polymorphisms and association analysis with insulin action in Pima Indians.