PPME1 Antibodies

AND PPME1 ELISA kits, PPME1 Proteins

Many biological assays use antibodies to detect PPME1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPME1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPME1 antibodies...

We validate the specificity of these antibodies to PPME1 by testing them on tissues known to express PPME1 positively and negatively. Browse below to find the PPME1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPME1 Infographic by Boster Bio

All PPME1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

PPME1 (NM_016147) Human Recombinant Protein

$813
Cat # PROTQ9Y570
20 µg

Anti-PPME1 Mouse Monoclonal Antibody [Clone ID: OTI7F12]

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M08083
100 µl

PPME1 (NM_016147) Human Over-expression Lysate

Human

$628
Cat # LS051400
100 µg

PPME1 Overview

Facts about Protein phosphatase methylesterase 1.

PPME1 3D structure. Source: alphafold

Protein phosphatase methylesterase 1 (PPME1)

Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA.

Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. .

Gene Information

Human
Gene Name:	PPME1
Uniprot:	Q9Y570
Entrez:	51400

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

EC 3.1.1; EC 3.1.1.-; FLJ22226; PME-1PME1; protein phosphatase methylesterase 1; protein phosphatase methylesterase-1

Molecular Weight

Mass (kDA):
42.315 kDA

Genomic Context


Human

Location:	11q13.4
Sequence:	11; NC_000011.10 (74171090..74254703)

Diseases

Alzheimer's Disease
Neurofibrillary Tangles

Pathways

Hyperphosphorylation

PTMs

Phosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPME1

References

PMID: 10318862 by Ogris E., et al. A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A.

PMID: 18394995 by Xing Y., et al. Structural mechanism of demethylation and inactivation of protein phosphatase 2A.