PPIC Antibodies

AND PPIC ELISA kits, PPIC Proteins

Many biological assays use antibodies to detect PPIC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPIC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPIC antibodies...

We validate the specificity of these antibodies to PPIC by testing them on tissues known to express PPIC positively and negatively. Browse below to find the PPIC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPIC Infographic by Boster Bio

All PPIC Products

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Product

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Specificity

Applications

Price

Anti-PPIC Antibody

Human

$405
Cat # A11281
100ul

PPIC (NM_000943) Human Recombinant Protein

$813
Cat # PROTP45877
20 µg

PPIC Overview

Facts about Peptidyl-prolyl cis-trans isomerase C.

PPIC 3D structure. Source: alphafold

Peptidyl-prolyl cis-trans isomerase C (PPIC)

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. .

Gene Information

Human
Gene Name:	PPIC
Uniprot:	P45877
Entrez:	5480

Family

Belongs to:

cyclophilin-type PPIase family

Alternative Names

Cyclophilin C; CYPCMGC3673; EC 5.2.1.8; parvulin; peptidyl-prolyl cis-trans isomerase C; peptidylprolyl isomerase C (cyclophilin C); PPIase C; Rotamase C

Molecular Weight

Mass (kDA):
22.763 kDA

Genomic Context


Human

Location:	5q23.2
Sequence:	5; NC_000005.10 (123023250..123036725, complement)

Tissue Specificity

Expressed in kidney, skeletal muscle, pancreas, heart, lung, liver and to a lower extent in brain.

Subcellular Localizations

Cytoplasm.

Diseases

Disseminated Intravascular Coagulation
Malignant Neoplasms
Neoplasms
Thrombophilia
Leukemia
Thrombosis
Pulmonary Embolism
Systemic Infection
Embolism
Neoplasm Metastasis
Venous Thrombosis
Hemorrhage

Thrombocytopenic Purpura
Hematologic Neoplasms
Acute Myocardial Infarction
Infarction
Multiple Organ Failure
Purpura, Thrombotic Thrombocytopenic
Myocardial Infarction

Interacting Proteins

BANP
SGTA
UBAP1
UBQLN1

Pathways

Coagulation
Fibrinolysis
Pathogenesis
Blood Coagulation
Hemostasis
Methylation
Gastric Emptying

Excretion
Secretion

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPIC

References

PMID: 8031755 by Schneider H., et al. Human cyclophilin C: primary structure, tissue distribution, and determination of binding specificity for cyclosporins.

PMID: 20676357 by Davis T.L., et al. Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.