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- Table of Contents
Facts about Peptidyl-prolyl cis-trans isomerase A.
.
Human | |
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Gene Name: | PPIA |
Uniprot: | P62937 |
Entrez: | 5478 |
Belongs to: |
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cyclophilin-type PPIase family |
Cyclophilin A; Cyclosporin A-binding protein; CYPA; CYPAMGC12404; CYPH; EC 5.2.1.8; MGC117158; MGC23397; peptidyl-prolyl cis-trans isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase A; Rotamase A; Rotamase; T cell cyclophilin
Mass (kDA):
18.012 kDA
Human | |
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Location: | 7p13 |
Sequence: | 7; NC_000007.14 (44795960..44803117) |
Cytoplasm. Secreted. Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
PMID: 3297675 by Haendler B., et al. Complementary DNA for human T-cell cyclophilin.
PMID: 2197089 by Haendler B., et al. Characterization of the human cyclophilin gene and of related processed pseudogenes.