Liprin-alpha-2 Antibodies

AND PPFIA2 ELISA kits, Liprin-alpha-2 Proteins

Many biological assays use antibodies to detect Liprin-alpha-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Liprin-alpha-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Liprin-alpha-2 antibodies...

We validate the specificity of these antibodies to Liprin-alpha-2 by testing them on tissues known to express PPFIA2 positively and negatively. Browse below to find the PPFIA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPFIA2 Infographic by Boster Bio

All PPFIA2 Products

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Specificity

Applications

Price

Liprin alpha 2 (PPFIA2) (NM_003625) Human Over-expression Lysate

Human

$960
Cat # LS008499
100 µg

Anti-PPFIA2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A11773
100 µg/vial

PPFIA2 Overview

Facts about Liprin-alpha-2.

PPFIA2 3D structure. Source: alphafold

Liprin-alpha-2 (PPFIA2)

Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions.

May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. .

Gene Information

Human
Gene Name:	PPFIA2
Uniprot:	O75334
Entrez:	8499

Family

Belongs to:

liprin family

Alternative Names

Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 2; PTPRF interacting protein alpha 2

Molecular Weight

Mass (kDA):
143.291 kDA

Genomic Context


Human

Location:	12q21.31
Sequence:	12; NC_000012.12 (81257975..81759749, complement)

Tissue Specificity

Expressed only in brain.

Subcellular Localizations

Cytoplasm. Cell surface. Cell projection, dendritic spine. Colocalizes with PTPRF at the cell surface.

Diseases

Tissue Adhesions
Malignant Neoplasm Of Prostate
Adenocarcinoma
Varicosity
Malignant Neoplasms
Neoplasms, Hormone-dependent
Prostatic Neoplasms
Neoplasms

Nervousness
Shwachman Syndrome

Pathways

Cell Adhesion
Cell Migration
Axon Guidance
Synaptic Transmission
Vesicle Docking
Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPFIA2

References

PMID: 9624153 by Serra-Pages C., et al. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins.