PPA2 Antibodies

Inorganic pyrophosphatase 2, mitochondrial (PPA2)

Hydrolyzes inorganic pyrophosphate (PubMed:27523597). This activity is essential for proper regulation of mitochondrial membrane potential, and mitochondrial organization and function (PubMed:27523598).

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Gene Information

Human
Gene Name:	PPA2
Uniprot:	Q9H2U2
Entrez:	27068

Family

Belongs to:
PPase family

Alternative Names

EC 3.6.1.1; FLJ20459; MGC49850; mitochondrial; pyrophosphatase (inorganic) 2

Molecular Weight

Mass (kDA):
37.92 kDA

Genomic Context

Human
Location:	4q24
Sequence:	4; NC_000004.12 (105369077..105474070, complement)

Tissue Specificity

Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.

Subcellular Localizations

Mitochondrion.

Diseases

• Neoplasm Metastasis
• Malignant Neoplasms
• Neoplasms
• Malignant Neoplasm Of Prostate
• Atherosclerosis
• Prostatic Neoplasms
• Mitochondrial Dna Depletion
• Hepatitis, Chronic
• Metastatic Malignant Neoplasm To The Lymph Node
• Hepatitis C, Chronic
• Benign Prostatic Hypertrophy
• Carcinoma

• Hypokinesia
• Insulin Resistance
• Immunologic Deficiency Syndromes
• Cardiovascular Diseases
• Metastatic Prostate Cancer
• Nervousness
• Dysmyelopoietic Syndromes

Pathways

• Cell Cycle
• Cytokinesis
• Mitosis
• Transport
• Cell Division
• Interphase
• Cell Growth
• Protein Phosphorylation
• Hyperphosphorylation
• Habituation
• Virulence
• Anaphase
• Cell Cycle Arrest

• Reverse Transcription
• Regulation Of Mitosis
• Mating
• Cell Morphogenesis
• Regulation Of Cytokinesis
• Exocytosis
• Hormone Secretion

PTMs

• Phosphorylation

• Hydroxylation

Research Areas

• Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPA2

Boster Bio - Best Uses Of The PPA2 Marker

You need to know how to optimize flow procedures in order to get the most from your Boster Bio. There are many options. It is important that you optimize your experiments to maximize their impact. Boster Bio has many tips and tricks that can help you make the most of your experiment. This powerful tool can help you optimize your experiments.

pGEX Grb2SH2-SH3

The SH2 domain in the pGEX Grb2 SH2-Sh3 marker has extensive flexibility for target recognition. The crystal structure of Grb2 at 2.0-A resolution reveals extensive flexibility for target recognition. The native protein sequences, and structures, are close to optimal. The SH3 domain of Grb2 is also close to its optimal structure. The pp60cc-src catalyticdomain recognizes the structural characteristics of the synthesized protein. The RRsrc peptide can be used as a substrate for tyrosine kinases. A solution structure was also found for the HIV-1 NEF protein. The solution structure was refined against J-couplings, NOEs, and 1H/13C chemical shifts.

For the analysis the SH2domain, there are many methods of gene transcription analysis. The Hck tyrosine-kinase SH3domain interacts with proteins that contain proline-rich areas. It mediates tight association between Hck and receptor protein tyrosinephosphatase beta. The Hck domain acts as a regulatory element in the binding between the two proteins.

pGEX-5X-1-LARP7

You want to find the best primary antibodies for your PPA2 Marker. Boster is a trusted source for quality antibodies. They have been producing antibodies for over 25-years. Boster primary antibodies are available for all purposes, including studying the PPA2 Marker or searching for an IHC specific antibody.

pGEX-6P-1-RIPK3

The PPA2 antibody marker is a potent, immunoreactive protein implicated in a number of diseases. It is a very potent analyte, which can be used to perform various experiments for its antioxidant and anti-inflammatory properties. Boster Bio provides high-affinity primary antibodies that are validated for use in immunohistochemistry and Western blotting.