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- Table of Contents
Facts about POU domain, class 6, transcription factor 1.
.
Human | |
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Gene Name: | POU6F1 |
Uniprot: | Q14863 |
Entrez: | 5463 |
Belongs to: |
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POU transcription factor family |
Brain-specific homeobox/POU domain protein 5; Brn-5; BRN5brain-5; mPOU homeobox protein; MPOUbrn-5; POU class 6 homeobox 1; POU domain, class 6, transcription factor 1; TCFB1Brain-5
Mass (kDA):
32.645 kDA
Human | |
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Location: | 12q13.13 |
Sequence: | 12; NC_000012.12 (51186936..51219875, complement) |
In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum.
Nucleus.
PMID: 7908264 by Wey E., et al. A human POU domain gene, mPOU, is expressed in developing brain and specific adult tissues.
PMID: 8102789 by Messier H., et al. A novel POU domain protein which binds to the T-cell receptor beta enhancer.