POU3F4 Antibodies

AND POU3F4 ELISA kits, POU3F4 Proteins

Many biological assays use antibodies to detect POU3F4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POU3F4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POU3F4 antibodies...

We validate the specificity of these antibodies to POU3F4 by testing them on tissues known to express POU3F4 positively and negatively. Browse below to find the POU3F4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POU3F4 Infographic by Boster Bio

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BRN4 (POU3F4) (NM_000307) Human Recombinant Protein

$813
Cat # PROTP49335
20 µg

POU3F4 Overview

Facts about POU domain, class 3, transcription factor 4.

POU3F4 3D structure. Source: alphafold

POU domain, class 3, transcription factor 4 (POU3F4)

Probable transcription factor that exert its primary activity widely during early neural development and in a very limited set of neurons in the mature brain. .

Gene Information

Human
Gene Name:	POU3F4
Uniprot:	P49335
Entrez:	5456

Family

Belongs to:

POU transcription factor family

Alternative Names

brain-specific homeobox/POU domain protein 4; octamer-binding transcription factor 9; OTF9; POU class 3 homeobox 4; POU domain, class 3, transcription factor 4

Molecular Weight

Mass (kDA):
39.427 kDA

Genomic Context


Human

Location:	Xq21.1
Sequence:	X; NC_000023.11 (83508290..83512127)

Tissue Specificity

Brain specific.

Subcellular Localizations

Nucleus.

Diseases

Complete Hearing Loss
Sensorineural Hearing Loss (disorder)
Hearing Loss, Mixed Conductive-sensorineural
Genetic Diseases, X-linked
Dysplasia
Deafness Congenital
Conductive Hearing Loss
Choroideremia
Sex Chromosome Aberrations
Nervousness
Neoplasms
Congenital Abnormality

Cytogenetic Abnormality
Hearing Problem
Hearing Loss, Bilateral
Chromosome Inversion
Congenital Ear Anomaly Nos (disorder)
Norrie Disease

Pathways

Ear Development
Inner Ear Development
Localization
Glucose Homeostasis
Methylation
Regeneration
Pathogenesis
Transport
Response To Camp
Stem Cell Differentiation
Neurogenesis
Regulation Of Gene Expression
Pancreatic Bud Formation

Reverse Transcription
Mrna Transcription
Cell Differentiation
Potassium Ion Homeostasis
Bone Mineralization
Cell Proliferation
Pancreas Development

PTMs

Methylation

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POU3F4

References

PMID: 7839145 by de Kok Y.J.M., et al. Association between X-linked mixed deafness and mutations in the POU domain gene POU3F4.

PMID: 9105675 by Malik K.F., et al. The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.