POU2AF1 Antibodies

AND POU2AF1 ELISA kits, POU2AF1 Proteins

Many biological assays use antibodies to detect POU2AF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POU2AF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POU2AF1 antibodies...

We validate the specificity of these antibodies to POU2AF1 by testing them on tissues known to express POU2AF1 positively and negatively. Browse below to find the POU2AF1 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POU2AF1 Infographic by Boster Bio

All POU2AF1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-BOB1/POU2AF1 Antibody Picoband®

1 Q&As

Mouse, Rat

IHC, WB

$370
Cat # PA1506
100 μg/vial

Anti-BOB1 Monoclonal Antibody

Human, Rat

IP, IHC, WB

$370
Cat # M04431
100 μl

Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378

Human

IHC, WB

$431
Cat # M04431-1
100uL

Anti-Bob 1 POU2AF1 Antibody

Human

ELISA, IHC

$380
Cat # A04431-1
100ul

Human POU2AF1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ16633
Starting from 10ug

Anti-BOB1 (POU2AF1) Mouse Monoclonal Antibody [Clone ID: OTI2D3]

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M04431-2
100 µl

Anti-BOB1 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M04431-3
100 μl/vial

BOB1 (POU2AF1) (NM_006235) Human Over-expression Lysate

Human

$628
Cat # LS005450
100 µg

POU2AF1 Overview

Facts about POU domain class 2-associating factor 1.

POU2AF1 3D structure. Source: alphafold

POU domain class 2-associating factor 1 (POU2AF1)

Transcriptional coactivator that specifically associates with OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2.

It has no intrinsic DNA-binding activity. It admits the POU domains of OCT1 and OCT2.

Gene Information

Human
Gene Name:	POU2AF1
Uniprot:	Q16633
Entrez:	5450

Family

Belongs to:

POU2AF1 family

Alternative Names

B-cell-specific coactivator OBF-1; BOB-1; OBF-1; OBF1BOB1; OCAB; OCA-B; OCT-binding factor 1; POU class 2 associating factor 1; POU domain class 2, associating factor 1; POU domain class 2-associating factor 1; POU domain, class 2, associating factor 1

Molecular Weight

Mass (kDA):
27.436 kDA

Genomic Context


Human

Location:	11q23.1
Sequence:	11; NC_000011.10 (111352251..111379671, complement)

Tissue Specificity

B-cell specific.

Subcellular Localizations

Nucleus.

Diseases

Lymphoma
Hodgkin Disease
B-cell Lymphomas
Neoplasms
Classical Hodgkin's Lymphoma
Diffuse Large B-cell Lymphoma
Leukemia
Nodular Lymphocyte Predominant Hodgkin Lymphoma
Lymphoma, Non-hodgkin
Malignant Neoplasms
Chromosomal Translocation
Plasmacytoma
Ki-1+ Anaplastic Large Cell Lymphoma

T-cell Lymphoma
Multiple Myeloma
Cell Transformation, Neoplastic
Autoimmunity
Burkitt Lymphoma
Hematologic Neoplasms
Malignant Paraganglionic Neoplasm

Interacting Proteins

SIAH1

Pathways

Cell Development
Germinal Center Formation
Cell Differentiation
B Cell Differentiation
Immune Response
Cell Maturation
Pathogenesis
Cell Activation
B Cell Activation
Immunoglobulin Production
Localization
Secretion
Cell Cycle

Cell Proliferation
Methylation
Lymphocyte Differentiation
Cell Adhesion
Mature B Cell Differentiation
Gene Silencing
Dna Recombination

PTMs

Phosphorylation
Myristoylation

Deamination
Deacetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POU2AF1

References

PMID: 7859290 by Strubin M., et al. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer- binding proteins.

PMID: 7779176 by Gstaiger M., et al. A B-cell coactivator of octamer-binding transcription factors.