POLR3K Antibodies

AND POLR3K ELISA kits, POLR3K Proteins

Many biological assays use antibodies to detect POLR3K, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLR3K in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLR3K antibodies...

We validate the specificity of these antibodies to POLR3K by testing them on tissues known to express POLR3K positively and negatively. Browse below to find the POLR3K antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POLR3K Infographic by Boster Bio

All POLR3K Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-POLR3K Antibody

Human, Mouse, Rat

$405
Cat # A13998
100ul

POLR3K (NM_016310) Human Recombinant Protein

$813
Cat # PROTQ9Y2Y1
20 µg

POLR3K (NM_016310) Human Over-expression Lysate

Human

$628
Cat # LS051728
100 µg

POLR3K Overview

Facts about DNA-directed RNA polymerase III subunit RPC10.

POLR3K 3D structure. Source: alphafold

DNA-directed RNA polymerase III subunit RPC10 (POLR3K)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.

Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune reaction.

Gene Information

Human
Gene Name:	POLR3K
Uniprot:	Q9Y2Y1
Entrez:	51728

Family

Belongs to:

archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family

Alternative Names

C11; DNA-directed RNA polymerase III subunit K; DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerases III 12.5 kDa polypeptide; hRPC11; HsC11p; polymerase (RNA) III (DNA directed) polypeptide K (12.3 kDa); polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit (hRPC11); RNA polymerase III subunit C10; RNA polymerase III subunit C11; RNA polymerase III subunit CII; RPC10; RPC11C11-RNP3; RPC12.5

Molecular Weight

Mass (kDA):
12.336 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (46407..53608, complement)

Subcellular Localizations

Nucleus, nucleolus.

Pathways

Organ Development

PTMs

Cleavage

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLR3K

References

PMID: 9869639 by Chedin S., et al. The RNA cleavage activity of RNA polymerase III is mediated by an essential TFIIS-like subunit and is important for transcription termination.

PMID: 10079944 by Spakovskii G.V., et al. Molecular identification and characteristics of hRPC11, the smallest specific subunit of human RNA polymerase III.