POLR2K Antibodies

AND POLR2K ELISA kits, POLR2K Proteins

Many biological assays use antibodies to detect POLR2K, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLR2K in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLR2K antibodies...

We validate the specificity of these antibodies to POLR2K by testing them on tissues known to express POLR2K positively and negatively. Browse below to find the POLR2K antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POLR2K Infographic by Boster Bio

All POLR2K Products

Product

Figures

Specificity

Applications

Price

Human POLR2K Recombinant Protein

SDS-PAGE

$265
Cat # PROTP53803
Starting from 10ug

POLR2K (NM_005034) Human Over-expression Lysate

Human

$628
Cat # LS005440
100 µg

POLR2K Overview

Facts about DNA-directed RNA polymerases I, II, and III subunit RPABC4.

POLR2K 3D structure. Source: alphafold

DNA-directed RNA polymerases I, II, and III subunit RPABC4 (POLR2K)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common part of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.

Gene Information

Human
Gene Name:	POLR2K
Uniprot:	P53803
Entrez:	5440

Family

Belongs to:

archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family

Alternative Names

ABC10-alpha; DNA directed RNA polymerases I, II, and III 7.0 kda polypeptide; DNA-directed RNA polymerase II subunit K; DNA-directed RNA polymerases I, II, and III subunit RPABC4; hRPB7.0; hsRPB10a; polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa; RNA polymerase II 7.0 kDa subunit; RNA polymerases I, II, and III subunit ABC4; RPABC4; RPB10alphapolymerase (RNA) II (DNA directed) polypeptide K (7.0kD); RPB12; RPB7.0

Molecular Weight

Mass (kDA):
7.004 kDA

Genomic Context


Human

Location:	8q22.2
Sequence:	8; NC_000008.11 (100150636..100154003)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Carcinoma
Carcinoma, Transitional Cell
Cell Transformation, Neoplastic
Malignant Neoplasms
Liver Carcinoma
Liver Neoplasms
Cytogenetic Abnormality

Carcinogenesis
Chemical Carcinogenesis

Pathways

Cell Proliferation

Research Areas

DNA Repair
DNA replication, Transcription, Translation and Splicing

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLR2K

References

PMID: 7651387 by Shpakovski G.V., et al. Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae.