POLR2J Antibodies

AND POLR2J ELISA kits, POLR2J Proteins

Many biological assays use antibodies to detect POLR2J, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLR2J in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLR2J antibodies...

We validate the specificity of these antibodies to POLR2J by testing them on tissues known to express POLR2J positively and negatively. Browse below to find the POLR2J antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POLR2J Infographic by Boster Bio

All POLR2J Products

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Product

Figures

Specificity

Applications

Price

Anti-RPB11 POLR2J Antibody

1 Q&As

Human, Mouse

ELISA, WB

$335
Cat # A30650
100ul

Human POLR2J Recombinant Protein

SDS-PAGE

$250
Cat # PROTP52435
Starting from 10ug

Anti-RPB11 (POLR2J) Mouse Monoclonal Antibody [Clone ID: OTI1B11]

Human, Mouse, Rat

$523
Cat # M11442
100 µl

RPB11 (POLR2J) (NM_006234) Human Over-expression Lysate

Human

$628
Cat # LS005439
100 µg

POLR2J Overview

Facts about DNA-directed RNA polymerase II subunit RPB11-a.

POLR2J 3D structure. Source: alphafold

DNA-directed RNA polymerase II subunit RPB11-a (POLR2J)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and lots of functional non-coding RNAs.

Pol II is the central part of the basal RNA polymerase II transcription machinery. It's composed of mobile elements that move relative to one another.

Gene Information

Human
Gene Name:	POLR2J
Uniprot:	P52435
Entrez:	5439

Family

Belongs to:

archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family

Alternative Names

DNA-directed RNA polymerase II subunit J-1; DNA-directed RNA polymerase II subunit RPB11-a; hRPB14; MGC71910; POLR2J1RNA polymerase II subunit B11-a; polymerase (RNA) II (DNA directed) polypeptide J (13.3kD); polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa; RNA polymerase II 13.3 kDa subunit; RPB11; RPB11A; RPB11m

Molecular Weight

Mass (kDA):
13.293 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (102473094..102478934, complement)

Tissue Specificity

Ubiquitously expressed. High expression was found in heart and skeletal muscle.

Subcellular Localizations

Nucleus.

Diseases

Sclerosis
Malignant Neoplasms
Multiple Sclerosis
Lung Neoplasms
Neoplasms
Non-small Cell Lung Carcinoma
Inflammation

Malignant Neoplasm Of Lung
Hypokinesia

Interacting Proteins

POLR1C

Pathways

Localization
Transport
Hyperphosphorylation
Translation
Mrna Transport
Pathogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLR2J

References

PMID: 8797801 by Fanciulli M., et al. Cloning of a novel human RNA polymerase II subunit downregulated by doxorubicin: new potential mechanisms of drug related toxicity.

PMID: 9201987 by Acker J., et al. Interactions between the human RNA polymerase II subunits.