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POLR2F Antibodies
AND POLR2F ELISA kits, POLR2F Proteins
Many biological assays use antibodies to detect POLR2F, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLR2F in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLR2F antibodies...
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POLR2F Infographic by Boster Bio
All POLR2F Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$523
Cat # M10044
100 µl
Cat # M10044
100 µl
POLR2F Overview
Facts about DNA-directed RNA polymerases I, II, and III subunit RPABC2.
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (POLR2F)
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common part of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and lots of functional non-coding RNAs, and smaller RNAs, such as 5S rRNA and tRNAs, respectively.
Pol II is the central part of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other.
Gene Information
| Human | |
|---|---|
| Gene Name: | POLR2F |
| Uniprot: | P61218 |
| Entrez: | 5435 |
Family
| Belongs to: |
|---|
| archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family |
Alternative Names
DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; HRBP14.4; II, and III subunit RPABC2; polymerase (RNA) II (DNA directed) polypeptide F; RNA Polymerase II subunit 14.4 kD; RNA polymerases I, II, and III subunit ABC2; RPB6 homolog; RPB6
Molecular Weight
Mass (kDA):
14.478 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q13.1 |
| Sequence: | 22; NC_000022.11 (37953663..38041915) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neuroblastoma
- Adenocarcinoma
- Neoplasm Metastasis
- Lung Neoplasms
- Metastatic Malignant Neoplasm To The Lung
- Breast Adenocarcinoma
- Hypoxia
- Fish Diseases
- Carcinoma
- Carcinogenesis
Pathways
- Translation
- Cell Cycle
PTMs
- Acetylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLR2F
bosterbio.com/bosterbio-gene-info-cards/POLR2F
References
PMID: 7803819 by Acker J., et al. A 14.4 KDa acidic subunit of human RNA polymerase II with a putative leucine-zipper.
PMID: 8786150 by Pusch C., et al. Genomic structure of the RNA polymerase II small subunit (hRPB14.4) locus (POLRF) and mapping to 22q13.1 by sequence identity.