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- Table of Contents
Facts about DNA polymerase lambda.
Also contributes to DNA double-strand fracture repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240). Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195).
Human | |
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Gene Name: | POLL |
Uniprot: | Q9UGP5 |
Entrez: | 27343 |
Belongs to: |
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DNA polymerase type-X family |
BETAN; DNA polymerase beta-2; DNA polymerase beta-N; DNA polymerase kappa; DNA polymerase lambda; EC 2.7.7.7; EC 4.2.99.-; FLJ46002; Pol beta2; Pol Lambda; POLKAPPA; polymerase (DNA directed), lambda
Mass (kDA):
63.482 kDA
Human | |
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Location: | 10q24.32 |
Sequence: | 10; NC_000010.11 (101578882..101588319, complement) |
Expressed in a number of tissues. Abundant in testis.
Nucleus.
PMID: 10982892 by Aoufouchi S., et al. Two novel human and mouse DNA polymerases of the polX family.
PMID: 10887191 by Nagasawa K.I., et al. Identification and characterization of human DNA polymerase beta 2, a DNA polymerase beta-related enzyme.