POLE2 Antibodies

AND POLE2 ELISA kits, POLE2 Proteins

Many biological assays use antibodies to detect POLE2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLE2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLE2 antibodies...

We validate the specificity of these antibodies to POLE2 by testing them on tissues known to express POLE2 positively and negatively. Browse below to find the POLE2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POLE2 Infographic by Boster Bio

All POLE2 Products

Product

Figures

Specificity

Applications

Price

Anti-DNA pol Epsilon 2 POLE2 Antibody

Human, Mouse, Rat

$405
Cat # A09182
100ul

POLE2 (NM_002692) Human Over-expression Lysate

Human

$960
Cat # LS005427
100 µg

Anti-POLE2 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A09182-2
100 µg/vial

POLE2 Overview

Facts about DNA polymerase epsilon subunit 2.

POLE2 3D structure. Source: alphafold

DNA polymerase epsilon subunit 2 (POLE2)

Participates in DNA repair and in chromosomal DNA replication. .

Gene Information

Human
Gene Name:	POLE2
Uniprot:	P56282
Entrez:	5427

Family

Belongs to:

DNA polymerase epsilon subunit B family

Alternative Names

DNA polymerase epsilon subunit 2; DNA polymerase II subunit 2; DPE2DNA polymerase epsilon subunit B; EC 2.7.7.7; polymerase (DNA directed), epsilon 2 (p59 subunit)

Molecular Weight

Mass (kDA):
59.537 kDA

Genomic Context


Human

Location:	14q21.3
Sequence:	14; NC_000014.9 (49643552..49688417, complement)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Liver Carcinoma
Lymphoma
Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse
Growth Arrest
Carcinoma

Interacting Proteins

AGFG1
EXOSC4
MAPRE1
POLE
REL

TBX15
TRIM27

Pathways

Cell Cycle
Cell Proliferation
S Phase
Cell Growth
Cell Cycle Arrest

PTMs

Phosphorylation

Research Areas

Core ESC-Like Genes
DNA Polymerases
DNA Repair
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLE2

References

PMID: 9405441 by Li Y., et al. Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon.

PMID: 9443964 by Jokela M., et al. The small subunits of human and mouse DNA polymerase epsilon are homologous to the second largest subunit of the yeast Saccharomyces cerevisiae DNA polymerase epsilon.