POC1B Antibodies

AND POC1B ELISA kits, POC1B Proteins

Many biological assays use antibodies to detect POC1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POC1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POC1B antibodies...

We validate the specificity of these antibodies to POC1B by testing them on tissues known to express POC1B positively and negatively. Browse below to find the POC1B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POC1B Infographic by Boster Bio

All POC1B Products

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Specificity

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Price

WDR51B (POC1B) (NM_172240) Human Recombinant Protein

$813
Cat # PROTQ8TC44
20 µg

WDR51B (POC1B) (NM_172240) Human Over-expression Lysate

Human

$628
Cat # LS282809
100 µg

POC1B Overview

Facts about POC1 centriolar protein homolog B.

POC1B 3D structure. Source: alphafold

POC1 centriolar protein homolog B (POC1B)

Plays an important part in centriole assembly and/or stability and ciliogenesis (PubMed:20008567). Involved in early steps of centriole duplication, as well as in the subsequent steps of centriole length control (PubMed:19109428).

Acts in concert with POC1A to guarantee centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length as well as cell proliferation (PubMed:23015594).

Gene Information

Human
Gene Name:	POC1B
Uniprot:	Q8TC44
Entrez:	282809

Family

Belongs to:

WD repeat POC1 family

Alternative Names

FLJ14923; FLJ41111; PIX1; POC1 centriolar protein homolog B (Chlamydomonas); POC1 centriolar protein homolog B; TUWD12; WD repeat domain 51B; WD repeat-containing protein 51B; WDR51B

Molecular Weight

Mass (kDA):
53.668 kDA

Genomic Context


Human

Location:	12q21.33
Sequence:	12; NC_000012.12 (89419718..89526047, complement)

Tissue Specificity

Expressed in the retina.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Component of both mother and daughter centrioles. Localizes to the basal body and centriole adjacent to the connecting cilium of photoreceptors and in synapses of the outer plexiform layer.

Interacting Proteins

NUDC

Pathways

Cell Cycle

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POC1B

References

PMID: 18068700 by Hames R.S., et al. Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells.

PMID: 20008567 by Pearson C.G., et al. Basal body stability and ciliogenesis requires the conserved component Poc1.